Urokinase

🧮 Dose calculator

Pulmonary embolism · Regimen source: FDA Kinlytic · Dosage and Administration

• • The calculator gives the loading dose; the maintenance infusion is the same amount per hour for 12 h. Start as soon as possible after PE onset. Afterwards, heparin without a bolus. FDA Kinlytic · Dosage and Administration

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Kinlytic · Pregnancy

  “Pregnancy Category B: Reproduction studies have been performed in mice and rats at doses up to 1,000 times the human dose and have revealed no evidence of impaired fertility or harm to the fetus due to Kinlytic™.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Kinlytic · Nursing Mothers

  “Because many drugs are excreted in human milk, caution should be exercised when Kinlytic™ is administered to a nursing woman.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Kinlytic · Pediatric Use

  “Safety and effectiveness in pediatric patients have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Kinlytic · Geriatric Use

  “Kinlytic™ should be used with caution in elderly patients.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.