Fluocinolone + hydroquinone + tretinoin cream

کرم سه‌گانه ملاسما (فلوسینولون + هیدروکینون + ترتینوئین)

⚠ Unverified

🧴 DermatologicalsDepigmenting combination

Market / country: 🇺🇸 USA

Tri-Luma (US)

🧮 Dose calculator

Melasma · Regimen source: FDA Tri-Luma · 2FDA Tri-Luma · 1

⛔ Once daily at least 30 min before bedtime, a thin film on the patches and about 1/2 inch of surrounding skin. Stop when controlled. Daytime SPF 30 sunscreen and sun avoidance. FDA Tri-Luma · 2FDA Tri-Luma · 1

🛡️ Safety & information

Contraindications

Warnings

  • • Contains sulfite (allergic reactions and asthma attacks in susceptible people). FDA Tri-Luma · 5

Formulations

  • Fluocinolone 0.01% / hydroquinone 4% / tretinoin 0.05% cream — cream 🇺🇸 USA FDA Tri-Luma · 3

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Tri-Luma · 8.1

    “Teratogenic Effects: Pregnancy Category C There are no adequate and well-controlled studies in pregnant women.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Tri-Luma · 8.3

    “Because many drugs are secreted in human milk, caution should be exercised when TRI-LUMA Cream is administered to a nursing woman.”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Tri-Luma · 8.4

    “Safety and effectiveness of TRI-LUMA Cream in pediatric patients have not been established.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Tri-Luma · 8.5

    “In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

📚 Reference status for this drug

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