Stiripentol

🧮 Dose calculator

Dravet syndrome · Regimen source: FDA Diacomit · 2.2, Table 1

• • ≥1 y and ≥10 kg: may use 3 doses (16.67 mg/kg). Round to the nearest achievable dose (usually within 50–150 mg of 50 mg/kg/day). With a meal; do not open capsules. CBC before starting. FDA Diacomit · 2.2FDA Diacomit · 2.3FDA Diacomit · 2.1

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Diacomit · 8.1

  “Risk Summary There are no adequate data on the developmental risks associated with the use of DIACOMIT in pregnant women.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Diacomit · 8.2

  “Risk Summary There are no data on the presence of stiripentol in human milk, the effects on the breastfed infant, or the effects on milk production.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Diacomit · 8.4

  “The safety and effectiveness of DIACOMIT have been established for the treatment of seizures associated with Dravet syndrome in patients taking clobazam who are 6 months and older and weighing 7 kg or more.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Diacomit · 8.5

  “Clinical studies of DIACOMIT in Dravet syndrome did not include patients ≥65 years of age to determine whether they respond differently from younger patients.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.