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Sodium zirconium cyclosilicate
سدیم زیرکونیوم سیکلوسیلیکات
🧪 VariousPotassium binder
🤰 Pregnancy:No specific problem stated🤱 Breastfeeding:No specific problem stated👶 Children:Safety not established👴 Older adults:No specific problem stated 🇮🇷 Not found in Iran list 🇺🇸 FDA approved (NDA) NDA207078ATC V03AE10
Market / country: 🇺🇸 USA
Lokelma (US)
🧮 Dose calculator
Hyperkalaemia · Regimen source: FDA Lokelma · 2.1
- • In about 3 tablespoons of water. Other oral drugs 2 h before or after. FDA Lokelma · 2.3
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Formulations
- 5 g sachet — sachet 🇺🇸 USA FDA Lokelma · 3
- 10 g sachet — sachet 🇺🇸 USA FDA Lokelma · 3
👥 Special populations
- 🤰 PregnancyNo specific problem stated
Label: minimal systemic absorption; fetal exposure not expected. FDA Lokelma · 8.1
“Risk Summary LOKELMA is not absorbed systemically following oral administration and maternal use is not expected to result in fetal exposure to the drug.”
- 🤱 BreastfeedingNo specific problem stated
Label: infant exposure not expected. FDA Lokelma · 8.2
“Risk Summary LOKELMA is not absorbed systemically following oral administration, and breastfeeding is not expected to result in exposure of the child to LOKELMA.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Lokelma · 8.4
“Safety and effectiveness in pediatric patients have not been established.”
- 👴 Older adultsNo specific problem stated
Label: no specific difference or dose adjustment stated for older adults. FDA Lokelma · 8.5
“No overall differences in safety or effectiveness were observed between these patients and younger patients.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA207078
- DailyMed (FDA label)FDA Lokelma
- MedlinePlus (NIH)Sodium Zirconium Cyclosilicate
- WHO ATC/DDDV03AE10
- Darooyab (Iran)❌ None
🇮🇷 Not found in Iran list Darooyab · search
Darooyab lists no registered dosage form or brand for this drug. This does not prove it is unavailable.
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Lokelma · 3FDA Lokelma · 2.1FDA Lokelma · 2.3FDA Lokelma · 2.2FDA Lokelma · 8.1FDA Lokelma · 8.2FDA Lokelma · 8.4FDA Lokelma · 8.5FDA Lokelma · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · search
- Clinical review⚠ Unverified