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Simvastatin
سیمواستاتین
❤️ CardiovascularStatin (HMG-CoA reductase inhibitor)
Market / country: 🇺🇸 USA
Zocor (US)
🧮 Dose calculator
Hyperlipidemia / heterozygous familial hypercholesterolemia · Regimen source: FDA Simvastatin · 2.2
- • Max recommended 40 mg; 80 mg only for patients on 80 mg ≥12 months without muscle toxicity. With amiodarone, amlodipine or ranolazine max 20 mg. Severe renal impairment: start 5 mg. FDA Simvastatin · 2.1FDA Simvastatin · 2.5FDA Simvastatin · 2.4
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ With strong CYP3A4 inhibitors (azoles, macrolides, antivirals, nefazodone), cyclosporine, danazol or gemfibrozil (and other items in section 4). FDA Simvastatin · 4
- ⛔ Not established under 10 years. FDA Simvastatin · 8.4
Formulations
- 5 mg tablet — tablet 🇺🇸 USA FDA Simvastatin · 3
- 10 mg tablet — tablet 🇺🇸 USA FDA Simvastatin · 3
- 20 mg tablet — tablet 🇺🇸 USA FDA Simvastatin · 3
- 40 mg tablet — tablet 🇺🇸 USA FDA Simvastatin · 3
- 80 mg tablet — tablet 🇺🇸 USA FDA Simvastatin · 3
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Simvastatin · 3FDA Simvastatin · 2.2FDA Simvastatin · 2.1FDA Simvastatin · 2.5FDA Simvastatin · 2.4FDA Simvastatin · 2.3FDA Simvastatin · 8.4FDA Simvastatin · 4
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Clinical review⚠ Unverified