Rifapentine

🧮 Dose calculator

Latent tuberculosis infection · Regimen source: FDA Priftin · 2.2, Table 1

• • Weekly isoniazid 15 mg/kg (≥12 y) or 25 mg/kg (2–11 y), max 900 mg. With meals. FDA Priftin · 2.2FDA Priftin · 2.3

Enter age and weight.

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Priftin · 8.1

  “Risk Summary Based on animal data, PRIFTIN may cause fetal harm when administered to a pregnant woman.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Priftin · 8.2

  “Risk Summary There are no data on the presence of rifapentine or its metabolite in human or animal milk, the effects on the breastfed infant, or the effects on milk production.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Priftin · 8.4

  “The safety and effectiveness of PRIFTIN in the treatment of active pulmonary tuberculosis have not been established in pediatric patients under the age of 12.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Priftin · 8.5

  “Clinical studies with PRIFTIN did not include sufficient numbers of subjects aged 65 years and over to determine whether they respond differently from younger subjects.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Priftin · 8.3

  “Contraception Use of PRIFTIN may reduce the efficacy of hormonal contraceptives.”