Rifabutin

🧮 Dose calculator

Disseminated Mycobacterium avium complex (MAC) in HIV · Regimen source: FDA Rifabutin · Dosage and Administration

• • If nausea: 150 mg twice daily with food. Never alone in active TB (resistance). With lopinavir/ritonavir reduce by at least 75%. FDA Rifabutin · Dosage and AdministrationFDA Rifabutin · WarningsFDA Rifabutin · Precautions

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Rifabutin · PREGNANCY

  “Rifabutin should be used in pregnant women only if the potential benefit justifies the potential risk to the fetus.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Rifabutin · NURSING MOTHERS

  “Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Rifabutin · PEDIATRIC USE

  “Safety and effectiveness of rifabutin for prophylaxis of MAC in children have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Rifabutin · GERIATRIC USE

  “In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy (see CLINICAL PHARMACOLOGY ).”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.