Rho(D) immune globulin (anti-D)
ایمونوگلوبولین Rh (آنتیD، رگام)
🦠 Antiinfectives For Systemic UseSpecific immune globulin
Market / country: 🇺🇸 USA
RhoGAM (US)
🧮 Dose calculator
Rh(D) isoimmunisation prophylaxis (Rh-negative mother) · Regimen source: FDA RhoGAM · 2.1
- • Pregnancy: 26–28 weeks. Postpartum (if newborn Rh-positive): within 72 h. Abortion, ectopic, invasive procedure or trauma after 13 weeks: within 72 h. Fetal-maternal haemorrhage >15 mL red cells: 20 mcg per mL of Rh-positive red cells, rounded up to the next whole syringe. FDA RhoGAM · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Rh-positive individuals; history of anaphylaxis or severe systemic reaction to human immune globulin. FDA RhoGAM · 4
Formulations
- 300 mcg (1500 IU) prefilled syringe — injection 🇺🇸 USA FDA RhoGAM · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA RhoGAM · 1.1
“RhoGAM is indicated for administration to Rh-negative women not previously sensitized to the Rho(D) factor, unless the father or baby are conclusively Rh-negative, in case of: Delivery of an Rh-positive baby irrespective of the ABO groups of the mother and baby Antepartum prophylaxis at 26 to 28 weeks gestation …”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA RhoGAM · 8.2
“Risk Summary RhoGAM can be used during breastfeeding.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA RhoGAM · 8.4
“Safety and effectiveness in pediatric patients have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA RhoGAM · 8.5
“No clinical studies have been performed in geriatric subjects.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)BLA103777
- DailyMed (FDA label)FDA RhoGAM
- MedlinePlus (NIH)❌ None
- WHO ATC/DDDJ06BB01
- Darooyab (Iran)Anti-D-Immunoglobulin-IM
🇮🇷 Registered in Iran Darooyab · G-3426/Anti-D-Immunoglobulin-IM
Dosage forms with Iranian generic codes, per Darooyab.
- 02370 · ANTI- D IMMUNE GLOBULIN 100MCG/2ML AMP · آمپول ضد–D ایمونوگلوبولین ۱۰۰ میکروگرم / ۲ میلیلیتر
- 01098 · ANTI- D IMMUNE GLOBULIN 250 MCG AMP · آمپول ضد–D ایمونوگلوبولین ۲۵۰ میکروگرم
- 01099 · ANTI- D IMMUNE GLOBULIN 300 MCG INJ · فرآورده تزریقی ضد–D ایمونوگلوبولین ۳۰۰ میکروگرم
- 52345 · ANTI-D IMMUNOGLOBULIN INJECTION, SOLUTION INTRAMUSCULAR 300 ug/2mL · فرآورده تزریقی ضد–D ایمونوگلوبولین ۳۰۰ میکروگرم / ۲ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA RhoGAM · 3FDA RhoGAM · 2.1FDA RhoGAM · 4FDA RhoGAM · 1.1FDA RhoGAM · 8.2FDA RhoGAM · 8.4FDA RhoGAM · 8.5FDA RhoGAM · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-3426/Anti-D-Immunoglobulin-IM
- Clinical review⚠ Unverified