Pyrazinamide
پیرازینامید
🦠 Antiinfectives For Systemic UseAntituberculous
Market / country: 🇺🇸 USA
Pyrazinamide (US)
🧮 Dose calculator
Tuberculosis · Regimen source: FDA Pyrazinamide · Dosage and Administration
- • Always with other TB drugs; CDC daily maximum 2 g. FDA Pyrazinamide · Dosage and Administration
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Severe hepatic damage; acute gout; hypersensitivity. FDA Pyrazinamide · Contraindications
Monitoring
- • Baseline and periodic uric acid and liver tests. FDA Pyrazinamide · Warnings
Formulations
- 500 mg tablet (scored) — tablet 🇺🇸 USA FDA Pyrazinamide · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Pyrazinamide · PREGNANCY
“Teratogenic Effects – Pregnancy Category C Animal reproduction studies have not been conducted with pyrazinamide.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Pyrazinamide · NURSING MOTHERS
“Pyrazinamide has been found in small amounts in breast milk.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Pyrazinamide · PEDIATRIC USE
“Pyrazinamide regimens employed in adults are probably equally effective in pediatric patients. 4, 10, 11 Pyrazinamide appears to be well tolerated in pediatric patients.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Pyrazinamide · GERIATRIC USE
“In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic or renal function, and of concomitant disease or other drug therapy.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA080157
- DailyMed (FDA label)FDA Pyrazinamide
- MedlinePlus (NIH)Pyrazinamide
- WHO ATC/DDDJ04AK01
- Darooyab (Iran)Pyrazinamide
🇮🇷 Registered in Iran Darooyab · G-488/Pyrazinamide
Dosage forms with Iranian generic codes, per Darooyab.
- 01078 · PYRAZINAMIDE 500MG TAB · قرص پیرازینامید ۵۰۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Pyrazinamide · How SuppliedFDA Pyrazinamide · Dosage and AdministrationFDA Pyrazinamide · ContraindicationsFDA Pyrazinamide · WarningsFDA Pyrazinamide · SPL approval / marketing categoryFDA Pyrazinamide · PREGNANCYFDA Pyrazinamide · NURSING MOTHERSFDA Pyrazinamide · PEDIATRIC USEFDA Pyrazinamide · GERIATRIC USE
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-488/Pyrazinamide
- Clinical review⚠ Unverified