Prucalopride

پروکالوپراید

⚠ Unverified

🍽️ Alimentary Tract And Metabolism5-HT4 receptor agonist

Market / country: 🇺🇸 USA

Motegrity (US)

🧮 Dose calculator

Chronic idiopathic constipation · Regimen source: FDA Motegrity · 2

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🛡️ Safety & information

Contraindications

  • ⛔ Hypersensitivity; intestinal perforation or obstruction, obstructive ileus, severe IBD (Crohn’s, colitis, toxic megacolon). FDA Motegrity · 4

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Motegrity · 8.1

    “Risk Summary Available data from case reports with prucalopride use in pregnant women are insufficient to identify any drug-associated risks of miscarriage, major birth defects, or adverse maternal or fetal outcomes.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Motegrity · 8.2

    “Risk Summary Prucalopride is present in breast milk (see Data ) .”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Motegrity · 8.4

    “The safety and effectiveness of MOTEGRITY have not been established in pediatric patients.”
  • 👴 Older adultsNo specific problem stated

    Label: no specific difference or dose adjustment stated for older adults. FDA Motegrity · 8.5

    “No overall differences in safety and effectiveness were observed between elderly and younger patients.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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Doz is only a support tool and does not replace clinical judgment or official sources. Check every dose against the original source before prescribing. About & disclaimer · Sources

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