Propofol

🧮 Dose calculator

General anaesthesia and premedication (adjunct) · Regimen source: FDA Diprivan · 2.7, Table 1FDA Diprivan · 2.2

• • Only by persons trained in anaesthesia, with airway management, oxygen and resuscitation available. FDA Diprivan · 2.1
• • Elderly, debilitated or ASA III/IV: 1–1.5 mg/kg; cardiac: 0.5–1.5; neurosurgical: 1–2 mg/kg. No rapid boluses in the elderly. FDA Diprivan · 2.7, Table 1

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Diprivan · 8.1

  “Risk Summary Data from randomized controlled trials, cohort studies and case series over several decades with propofol use in pregnant women have not identified a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Diprivan · 8.2

  “Risk Summary Based on data from published studies, propofol is present in human milk.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Diprivan · 8.4

  “The safety and effectiveness of DIPRIVAN have been established for induction of anesthesia in pediatric patients aged 3 years and older and for the maintenance of anesthesia aged 2 months and older.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Diprivan · 8.5

  “The effect of age on induction dose requirements for propofol was assessed in an open-label study involving 211 unpremedicated patients with approximately 30 patients in each decade between the ages of 16 and 80.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.