Pilocarpine 1.25% (presbyopia)
پیلوکارپین ۱٫۲۵٪ (پیرچشمی)
👁️ Sensory OrgansCholinergic (miotic)
Market / country: 🇺🇸 USA
Vuity (US)
🧮 Dose calculator
Presbyopia · Regimen source: FDA Pilocarpine 1.25% · 2
- • Separate other eye drops by at least 5 min. FDA Pilocarpine 1.25% · 2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to pilocarpine. FDA Pilocarpine 1.25% · 4
Warnings
- • Blurred vision and poor dim-light vision (caution driving at night); risk of retinal detachment; iritis. FDA Pilocarpine 1.25% · 5
Formulations
- 1.25% eye drops — eye drops 🇺🇸 USA FDA Pilocarpine 1.25% · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Pilocarpine 1.25% · 8.1
“Risk Summary There are no adequate and well-controlled studies of pilocarpine hydrochloride ophthalmic solution administration in pregnant women to inform a drug-associated risk.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Pilocarpine 1.25% · 8.2
“Risk Summary There is no information regarding the presence of pilocarpine in human milk, the effects on the breastfed infants or the effects on milk production to inform risk of pilocarpine hydrochloride ophthalmic solution to an infant during lactation.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Pilocarpine 1.25% · 8.4
“Presbyopia does not occur in the pediatric population.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Pilocarpine 1.25% · 8.5
“Clinical studies of pilocarpine hydrochloride ophthalmic solution did not include participants aged 65 and over to determine whether they respond differently from younger participants.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA217733
- DailyMed (FDA label)FDA Pilocarpine 1.25%
- MedlinePlus (NIH)❌ None
- WHO ATC/DDDS01EB01
- Darooyab (Iran)Pilocarpine
🇮🇷 Registered in Iran Darooyab · G-3052/Pilocarpine
Dosage forms with Iranian generic codes, per Darooyab.
- 01006 · PILOCARPINE 1% 10ML OPH DROP · قطره چشمی پیلوکارپین ۱ درصد ۱۰ میلیلیتر
- 01007 · PILOCARPINE 2% 10ML OPH DROP · قطره چشمی پیلوکارپین ۲ درصد ۱۰ میلیلیتر
- 01008 · PILOCARPINE 4% 10ML OPH DROP · قطره چشمی پیلوکارپین ۴ درصد ۱۰ میلیلیتر
- 06016 · PILOCARPINE 5MG TAB · قرص پیلوکارپین ۵ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Pilocarpine 1.25% · 3FDA Pilocarpine 1.25% · 2FDA Pilocarpine 1.25% · 4FDA Pilocarpine 1.25% · 5FDA Pilocarpine 1.25% · 8.1FDA Pilocarpine 1.25% · 8.2FDA Pilocarpine 1.25% · 8.4FDA Pilocarpine 1.25% · 8.5FDA Pilocarpine 1.25% · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-3052/Pilocarpine
- Clinical review⚠ Unverified