Phytonadione (vitamin K1)
ویتامین K1 (فیتونادیون)
🩸 Blood And Blood Forming OrgansVitamin K
Market / country: 🇺🇸 USA
AquaMephyton (US)
🧮 Dose calculator
Vitamin K deficiency bleeding / anticoagulant-induced hypoprothrombinaemia · Regimen source: FDA Phytonadione inj. · 2.3
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to phytonadione or components. FDA Phytonadione inj. · 4
Warnings
- • Boxed warning: severe hypersensitivity reactions and fatalities with IV and IM use; give SC whenever possible; IV no faster than 1 mg/min. FDA Phytonadione inj. · Boxed WarningFDA Phytonadione inj. · 2.1
Formulations
- 1 mg/0.5 mL prefilled syringe (neonatal) — injection 🇺🇸 USA FDA Phytonadione inj. · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Phytonadione inj. · 8.1
“Risk Summary If Phytonadione is needed during pregnancy, consider using a preservative-free formulation .”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Phytonadione inj. · 8.2
“Risk Summary If available, preservative-free Phytonadione is recommended when Phytonadione is needed during lactation [ Use in Specific Populations ( 8.4 )] .”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Phytonadione inj. · 8.4
“The safety and effectiveness of Phytonadione Injectable Emulsion for prophylaxis and treatment of vitamin K deficiency have been established in neonates.”
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA215820
- DailyMed (FDA label)FDA Phytonadione inj.
- MedlinePlus (NIH)PhytonadionePhytonadione Injection
- WHO ATC/DDDB02BA01
- Darooyab (Iran)Phytonadione
🇮🇷 Registered in Iran Darooyab · G-2954/Phytonadione
Dosage forms with Iranian generic codes, per Darooyab.
- 01856 · VITAMIN K 2MG AMP · آمپول ویتامین K ۲ میلیگرم
- 01003 · VITAMIN K1 (PHYTOMENADIONE) 10MG/1ML AMP · آمپول ویتامین K ۱ (فیتومنادیون) ۱۰ میلیگرم / ۱ میلیلیتر
- 01004 · VITAMIN K1 (PHYTOMENADIONE) 1MG/0.5ML AMP · آمپول ویتامین K ۱ (فیتومنادیون) ۱ میلیگرم / ۰٫۵ میلیلیتر
- 01005 · VITAMIN K1 (PHYTOMENADOINE) 10MG TAB · قرص ویتامین K ۱ (فیتومنادوین) ۱۰ میلیگرم
- 52467 · VITAMIN K1 (PHYTOMENADIONE) TABLET, CHEWABLE ORAL 10 mg · قرص جویدنی ویتامین K ۱ (فیتومنادیون) ۱۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Phytonadione inj. · 3FDA Phytonadione inj. · 2.3FDA Phytonadione inj. · 2.2FDA Phytonadione inj. · 4FDA Phytonadione inj. · Boxed WarningFDA Phytonadione inj. · 2.1FDA Phytonadione inj. · 8.1FDA Phytonadione inj. · 8.2FDA Phytonadione inj. · 8.4FDA Phytonadione inj. · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-2954/Phytonadione
- Clinical review⚠ Unverified