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Physostigmine
فیزوستیگمین
🧪 VariousCholinesterase inhibitor (antidote)
Market / country: 🇺🇸 USA
Anticholium (US)
🧮 Dose calculator
Anticholinergic toxicity · Regimen source: FDA Anticholium · Dosage and Administration
⛔ IV no faster than 1 mg/min; repeat every 10–30 min if needed. Ampoule concentration of this imported product is not stated in the available labeling; compute volume from the package. FDA Anticholium · Dosage and Administration
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity; asthma; gangrene; coronary heart disease; mechanical bowel or urinary obstruction; myotonic dystrophy; closed head injury; after depolarising relaxants (succinylcholine). FDA Anticholium · Contraindications
Formulations
- 5 mL ampoule (IM or slow IV) — injection 🇺🇸 USA FDA Anticholium · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Anticholium · Precautions/Warnings – Pregnancy
“and breast-feeding Pregnancy: There is no experience with the use of Anticholium ® in pregnant women.”
- 🤱 BreastfeedingNo data
The source for this drug has no section for this group.
- 👶 ChildrenNo data
The source for this drug has no section for this group.
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)❌ None
- DailyMed (FDA label)FDA Anticholium
- MedlinePlus (NIH)❌ None
- WHO ATC/DDDV03AB19
- Darooyab (Iran)Physostigmine
🇮🇷 Registered in Iran Darooyab · G-3051/Physostigmine
Dosage forms with Iranian generic codes, per Darooyab.
- 01638 · PHYSOSTIGMINE SAL 2MG/2ML AMP · آمپول فیسوستیگمین سال ۲ میلیگرم / ۲ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Anticholium · How SuppliedFDA Anticholium · Dosage and AdministrationFDA Anticholium · ContraindicationsFDA Anticholium · Precautions/Warnings – Pregnancy
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-3051/Physostigmine
- Clinical review⚠ Unverified