Pentoxifylline
پنتوکسیفیلین
❤️ Cardiovascular SystemXanthine derivative (haemorheologic)
Market / country: 🇺🇸 USA
Trental (US)
🧮 Dose calculator
Intermittent claudication (peripheral artery disease) · Regimen source: FDA Pentoxifylline ER · Dosage and Administration
- • Continue at least 8 weeks. With GI or CNS effects: 400 mg twice daily. CrCl <30: 400 mg once daily. FDA Pentoxifylline ER · Dosage and Administration
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Recent cerebral or retinal haemorrhage; intolerance to pentoxifylline or methylxanthines (caffeine, theophylline). FDA Pentoxifylline ER · Contraindications
Formulations
- 400 mg extended-release tablet — tablet 🇺🇸 USA FDA Pentoxifylline ER · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Pentoxifylline ER · Pregnancy
“There are no adequate and well controlled studies in pregnant women. pentoxifylline extended-release tablet should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Pentoxifylline ER · Nursing Mothers
“Pentoxifylline and its metabolites are excreted in human milk.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Pentoxifylline ER · Pediatric Use
“Safety and effectiveness in pediatric patients have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Pentoxifylline ER · Geriatric Use
“In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA018631
- DailyMed (FDA label)FDA Pentoxifylline ER
- MedlinePlus (NIH)Pentoxifylline
- WHO ATC/DDDC04AD03
- Darooyab (Iran)Pentoxifylline
🇮🇷 Registered in Iran Darooyab · G-1825/Pentoxifylline
Dosage forms with Iranian generic codes, per Darooyab.
- 07090 · PENTOXIFYLLINE 100MG INJ · فرآورده تزریقی پنتوکسیفیلین ۱۰۰ میلیگرم
- 07137 · PENTOXIFYLLINE 300MG INJ · فرآورده تزریقی پنتوکسیفیلین ۳۰۰ میلیگرم
- 00970 · PENTOXIFYLLINE 400MG TAB · قرص پنتوکسیفیلین ۴۰۰ میلیگرم
- 19809 · PENTOXIFYLLINE 600MG TAB · قرص پنتوکسیفیلین ۶۰۰ میلیگرم
- 18076 · PHENTOXIFYLINE 400 MG TAB. · قرص فنتوکسیفیلین ۴۰۰ میلیگرم .
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Pentoxifylline ER · How SuppliedFDA Pentoxifylline ER · Dosage and AdministrationFDA Pentoxifylline ER · ContraindicationsFDA Pentoxifylline ER · PregnancyFDA Pentoxifylline ER · Nursing MothersFDA Pentoxifylline ER · Pediatric UseFDA Pentoxifylline ER · Geriatric UseFDA Pentoxifylline ER · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1825/Pentoxifylline
- Clinical review⚠ Unverified