Pegfilgrastim
پگفیلگراستیم
🎗️ Antineoplastic And Immunomodulating AgentsLong-acting granulocyte colony-stimulating factor
Market / country: 🇺🇸 USA
Neulasta (US)
🧮 Dose calculator
Febrile neutropenia (empiric therapy) · Regimen source: FDA Neulasta · 2.1
- • Once per chemotherapy cycle; not between 14 days before and 24 hours after chemotherapy. FDA Neulasta · 2.1
- • Haematopoietic acute radiation syndrome: two 6 mg doses one week apart. FDA Neulasta · 2.2
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ History of serious hypersensitivity to pegfilgrastim or filgrastim. FDA Neulasta · 4
Warnings
- • Splenic rupture; ARDS; serious hypersensitivity; sickle-cell crises; glomerulonephritis; leukocytosis; capillary leak syndrome; MDS/AML. FDA Neulasta · 5
Formulations
- 6 mg/0.6 mL prefilled syringe (10 mg/mL) — injection 🇺🇸 USA FDA Neulasta · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Neulasta · 8.1
“Risk Summary Although available data with Neulasta use in pregnant women are insufficient to establish whether there is a drug associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes, there are available data from published studies in pregnant women exposed to filgrastim products.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Neulasta · 8.2
“Risk Summary There are no data on the presence of pegfilgrastim in human milk, the effects on the breastfed child, or the effects on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Neulasta · 8.4
“The safety and effectiveness of Neulasta for chemotherapy-induced neutropenia and hematopoietic subsyndrome of acute radiation syndrome have been established in pediatric patients.”
- 👴 Older adultsNo specific problem stated
Label: no specific difference or dose adjustment stated for older adults. FDA Neulasta · 8.5
“No overall differences in safety or effectiveness were observed between patients aged 65 and older and younger patients.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)BLA125031
- DailyMed (FDA label)FDA Neulasta
- MedlinePlus (NIH)Pegfilgrastim Injection
- WHO ATC/DDDL03AA13
- Darooyab (Iran)❌ None
🇮🇷 Not found in Iran list Darooyab · search
Darooyab lists no registered dosage form or brand for this drug. This does not prove it is unavailable.
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Neulasta · 3FDA Neulasta · 2.1FDA Neulasta · 2.2FDA Neulasta · 2.1, Table 1FDA Neulasta · 4FDA Neulasta · 5FDA Neulasta · SPL approval / marketing categoryFDA Neulasta · 8.1FDA Neulasta · 8.2FDA Neulasta · 8.4FDA Neulasta · 8.5
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · search
- Clinical review⚠ Unverified