Pancrelipase

🧮 Dose calculator

Exocrine pancreatic insufficiency · Regimen source: FDA Creon · 2.2

• • Half dose with snacks. Do not exceed 2,500 units/kg/meal or 10,000 units/kg/day without investigation (fibrosing colonopathy). Swallow capsules whole. FDA Creon · 2

Enter age and weight.

👥 Special populations

• 🤰 PregnancyNo specific problem stated

  Label: minimal systemic absorption; fetal exposure not expected. FDA Creon · 8.1

  “Pancrelipase is minimally absorbed systematically; therefore, maternal use is not expected to result in fetal exposure to the drug.”

• 🤱 BreastfeedingNo specific problem stated

  Label: infant exposure not expected. FDA Creon · 8.2

  “Pancrelipase is minimally absorbed systemically following oral administration; therefore, maternal use is not expected to result in clinically relevant exposure of breastfed infants to the drug.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Creon · 8.4

  “The safety and effectiveness of CREON for the treatment of exocrine pancreatic insufficiency have been established in pediatric patients.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Creon · 8.5

  “Clinical studies of CREON did not include sufficient numbers of patients aged 65 years and over to determine whether they respond differently from younger patients.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.