Naproxen

ناپروکسن

⚠ Unverified

🦴 Musculo-Skeletal SystemNSAID

Market / country: 🇺🇸 USA

Naprosyn (US)

🧮 Dose calculator

Mild to moderate pain · Regimen source: FDA Naproxen · 2.4

  • • First dose 500 mg, then 250 mg every 6–8 h as needed; max 1,250 mg/day. FDA Naproxen · 2.4

Enter age (weight is optional for this regimen).

🛡️ Safety & information

Contraindications

  • ⛔ Hypersensitivity; history of asthma, urticaria or allergic-type reaction after aspirin or other NSAIDs; in the setting of CABG surgery. FDA Naproxen · 4
  • ⚠️ Boxed warning: risk of serious cardiovascular thrombotic events and GI bleeding, ulceration and perforation. FDA Naproxen · Boxed Warning

Formulations

👥 Special populations

  • 🤰 PregnancyDangerous / avoid

    Label: can cause fetal harm. Dangerous in pregnancy. FDA Naproxen · 8.1

    “… losure of ductus arteriosus), use during pregnancy (particularly starting at 30-weeks of gestation, or third trimester) should be avoided.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Naproxen · 8.2

    “Risk Summary The naproxen anion has been found in the milk of lactating women at a concentration equivalent to approximately 1% of maximum naproxen concentration in plasma.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Naproxen · 8.4

    “Safety and effectiveness in pediatric patients below the age of 2 years have not been established.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Naproxen · Boxed Warning

    “Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events [ see Warnings and Precautions (5.2) ] .”
  • ⚥ Females & males of reproductive potentialUse with caution

    Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Naproxen · 8.3

    “Infertility Females Based on the mechanism of action, the use of prostaglandin-mediated NSAIDs, including naproxen tablets may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women.”

Doz is only a support tool and does not replace clinical judgment or official sources. Check every dose against the original source before prescribing. About & disclaimer · Sources

Inspired by the Saphira project; part of the content is taken from it.

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