Medroxyprogesterone injection (Depo)
مدروکسیپروژسترون تزریقی (دپو)
🚻 Genito Urinary System And Sex HormonesProgestin contraceptive
Market / country: 🇺🇸 USA
Depo-Provera CI (US)
🧮 Dose calculator
Contraception (combined pill) · Regimen source: FDA Depo-Provera CI · 2
- • Gluteal or deltoid muscle; shake vigorously before use. FDA Depo-Provera CI · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Active thrombophlebitis or history of thromboembolism or cerebrovascular disease; breast cancer; significant liver disease; undiagnosed vaginal bleeding; hypersensitivity. FDA Depo-Provera CI · 4
Warnings
- • Boxed warning: loss of bone mineral density; use beyond 2 years only if other methods are inadequate. FDA Depo-Provera CI · Boxed Warning
Formulations
- 150 mg/mL vial or prefilled syringe — injection 🇺🇸 USA FDA Depo-Provera CI · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Depo-Provera CI · 8.1
“Risk Summary There is no use for contraception in pregnancy; therefore, Depo-Provera CI should be discontinued during pregnancy.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Depo-Provera CI · 8.2
“Risk Summary Although medroxyprogesterone acetate is detectable in the milk of mothers receiving Depo-Provera CI, milk composition, quality, and amount do not appear to be adversely affected.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Depo-Provera CI · 8.4
“Depo-Provera CI is not indicated before menarche.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Depo-Provera CI · 8.5
“This product has not been studied in post-menopausal women and is not indicated in this population.”
- ⚥ Females & males of reproductive potentialUse with caution
Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Depo-Provera CI · 8.3
“Depo-Provera CI is indicated for the prevention of pregnancy and would therefore be expected to impair female fertility until cessation of treatment.”
🔗 Reference links
- FDA (approval record)NDA020246
- DailyMed (FDA label)FDA Depo-Provera CI
- MedlinePlus (NIH)Medroxyprogesterone Injection
- WHO ATC/DDDG03AC06
- Darooyab (Iran)Medroxyprogesterone-Acetate
🇮🇷 Registered in Iran Darooyab · G-3275/Medroxyprogesterone-Acetate
Dosage forms with Iranian generic codes, per Darooyab.
- 00791 · MEDROXYPROGESTERONE ACETATE 150MG/1ML AMP · آمپول مدروکسیپروژسترون استات ۱۵۰ میلیگرم / ۱ میلیلیتر
- 13657 · MEDROXYPROGESTERONE ACETATE 150MG/3ML VIAL · ویال مدروکسیپروژسترون استات ۱۵۰ میلیگرم / ۳ میلیلیتر
- 00789 · MEDROXYPROGESTERONE ACETATE 250MG TAB · قرص مدروکسیپروژسترون استات ۲۵۰ میلیگرم
- 00793 · MEDROXYPROGESTERONE ACETATE 500MG/2.5ML AMP · آمپول مدروکسیپروژسترون استات ۵۰۰ میلیگرم / ۲٫۵ میلیلیتر
- 00790 · MEDROXYPROGESTERONE ACETATE 500MG/5ML VIAL · ویال مدروکسیپروژسترون استات ۵۰۰ میلیگرم / ۵ میلیلیتر
- 00792 · MEDROXYPROGESTERONE ACETATE 5MG TAB · قرص مدروکسیپروژسترون استات ۵ میلیگرم
- 06066 · MEDROXYPROGESTRON 500MG/3.3ML VIAL · ویال مدروکسیپروجسترون ۵۰۰ میلیگرم / ۳٫۳ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Depo-Provera CI · 3FDA Depo-Provera CI · 2FDA Depo-Provera CI · 2.1FDA Depo-Provera CI · 4FDA Depo-Provera CI · Boxed WarningFDA Depo-Provera CI · 8.1FDA Depo-Provera CI · 8.2FDA Depo-Provera CI · 8.4FDA Depo-Provera CI · 8.5FDA Depo-Provera CI · 8.3FDA Depo-Provera CI · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-3275/Medroxyprogesterone-Acetate
- Clinical review⚠ Unverified