Hydroxocobalamin (Cyanokit)

🧮 Dose calculator

Cyanide poisoning · Regimen source: FDA Cyanokit · 2.2

• • Give without delay if suspicion is high. Depending on severity, a second 5 g dose (total 10 g) over 15 min to 2 h. Do not delay airway, oxygen and circulatory support. FDA Cyanokit · 2.2FDA Cyanokit · 2.1

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Cyanokit · 8.1

  “Risk Summary Available data from cases reported in the published literature and postmarketing surveillance with CYANOKIT use in pregnant women are insufficient to identify a drug-associated risk for major birth defects, miscarriage, or adverse maternal and fetal outcomes.”

• 🤱 BreastfeedingDangerous / avoid

  Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Cyanokit · 8.2

  “Risk Summary Breastfeeding is not recommended during treatment with CYANOKIT.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Cyanokit · 8.4

  “Safety and effectiveness of CYANOKIT have not been established in this population.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Cyanokit · 8.5

  “Approximately 50 known or suspected cyanide poisoning victims aged 65 or older received hydroxocobalamin in clinical studies.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.