Glucagon
گلوکاگون
🧬 Systemic Hormonal Preparations, Excl. Sex Hormones And InsulinsGlycogenolytic hormone (emergency)
Market / country: 🇺🇸 USA
Gvoke (US)
🧮 Dose calculator
Severe hypoglycaemia · Regimen source: FDA Gvoke (glucagon) · 2.1
- • ≥12 y: 1 mg. 2 to <12 y: <45 kg → 0.5 mg; ≥45 kg → 1 mg. If no response after 15 min, one more dose from a new device. FDA Gvoke (glucagon) · 2.1
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Pheochromocytoma; insulinoma; hypersensitivity to glucagon. FDA Gvoke (glucagon) · 4
- ⛔ Not labelled under 2 years. FDA Gvoke (glucagon) · 8.4
Formulations
- 0.5 mg/0.1 mL autoinjector — injection 🇺🇸 USA FDA Gvoke (glucagon) · 3
- 1 mg/0.2 mL autoinjector or syringe — injection 🇺🇸 USA FDA Gvoke (glucagon) · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Gvoke (glucagon) · 8.1
“Risk Summary Available data from case reports and a small number of observational studies with glucagon use in pregnant women over decades of use have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Gvoke (glucagon) · 8.2
“Risk Summary There is no information available on the presence of glucagon in human or animal milk, the effects of the drug on the breastfed infant, or the effects of the drug on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Gvoke (glucagon) · 8.4
“The safety and effectiveness of GVOKE for subcutaneous use for the treatment of severe hypoglycemia in patients with diabetes have been established in pediatric patients aged 2 years and older.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Gvoke (glucagon) · 8.5
“Clinical studies of GVOKE and GVOKE VialDx did not include sufficient numbers of patients aged 65 and over to determine whether they respond differently from younger adult patients.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA212097
- DailyMed (FDA label)FDA Gvoke (glucagon)
- MedlinePlus (NIH)Glucagon InjectionGlucagon Nasal Powder
- WHO ATC/DDDH04AA01
- Darooyab (Iran)Glucagon
🇮🇷 Registered in Iran Darooyab · G-1959/Glucagon
Dosage forms with Iranian generic codes, per Darooyab.
- 00597 · GLUCAGON HCL 1MG/1ML VIAL · ویال گلوکاگون هیدروکلراید ۱ میلیگرم / ۱ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Gvoke (glucagon) · 3FDA Gvoke (glucagon) · 2.1FDA Gvoke (glucagon) · 4FDA Gvoke (glucagon) · 8.4FDA Gvoke (glucagon) · 8.1FDA Gvoke (glucagon) · 8.2FDA Gvoke (glucagon) · 8.5FDA Gvoke (glucagon) · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1959/Glucagon
- Clinical review⚠ Unverified