Ganciclovir

🧮 Dose calculator

Cytomegalovirus (CMV) — retinitis and transplant prophylaxis · Regimen source: FDA Ganciclovir · 2.3FDA Ganciclovir · 2.4

• • Retinitis 14–21 days; transplant 7–14 days. 1-hour infusion, never bolus. FDA Ganciclovir · 2.3FDA Ganciclovir · 2.1

Enter age and weight.

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Ganciclovir · Boxed Warning

  “Fetal Toxicity: Based on animal data, ganciclovir has the potential to cause birth defects in humans [see Warnings and Precautions (5.4) ].”

• 🤱 BreastfeedingDangerous / avoid

  Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Ganciclovir · 8.2

  “Advise nursing mothers that breastfeeding is not recommended during treatment with ganciclovir because of the potential for serious adverse reactions in nursing infants [see Warnings and Precautions (5.1 , 5.3 , 5.4 , 5.5) , Nonclinical Toxicology (13.1) ].”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Ganciclovir · 8.4

  “Safety and efficacy of ganciclovir have not been established in pediatric patients.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Ganciclovir · 8.5

  “In general, dose selection for an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Ganciclovir · 8.3

  “Contraception Females Because of the mutagenic and teratogenic potential of ganciclovir, females of reproductive potential should be advised to use effective contraception during treatment and for at least 30 days following treatment with ganciclovir [see Dosage and Administration (2.2) , Warnings and Precautions …”