Fomepizole
فومپیزول
🧪 VariousAlcohol dehydrogenase inhibitor (antidote)
Market / country: 🇺🇸 USA
Antizol (US)
🧮 Dose calculator
Methanol or ethylene glycol poisoning · Regimen source: FDA Fomepizole · Dosage and Administration
- • First dose 15 mg/kg; then 10 mg/kg every 12 h for 4 doses; then 15 mg/kg every 12 h until methanol or ethylene glycol is undetectable or <20 mg/dL, the patient is asymptomatic and pH normal. Each dose over 30 min. Every 4 h during haemodialysis. Do not use polycarbonate syringes. Safety in children not established. FDA Fomepizole · Dosage and AdministrationFDA Fomepizole · Pediatric Use
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Serious hypersensitivity to fomepizole or other pyrazoles. FDA Fomepizole · Contraindications
Formulations
- 1 g/mL (1.5 g/1.5 mL) vial — dilute before infusion — injection 🇺🇸 USA FDA Fomepizole · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Fomepizole · Pregnancy:
“Pregnancy Category C: Animal reproduction studies have not been conducted with fomepizole.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Fomepizole · Nursing Mothers:
“Because many drugs are excreted in human milk, caution should be exercised when fomepizole is administered to a nursing woman.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Fomepizole · Pediatric Use:
“Safety and effectiveness in pediatric patients have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Fomepizole · Geriatric Use:
“Safety and effectiveness in geriatric patients have not been established.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA078537
- DailyMed (FDA label)FDA Fomepizole
- MedlinePlus (NIH)❌ None
- WHO ATC/DDDV03AB34
- Darooyab (Iran)Fomepizole
🇮🇷 Registered in Iran Darooyab · G-1957/Fomepizole
Dosage forms with Iranian generic codes, per Darooyab.
- 11908 · FOMEPIZOLE 1.5G/1.5ML VIAL · ویال فومپیزول ۱٫۵ گرم / ۱٫۵ میلیلیتر
- 53092 · FOMEPIZOLE (AS SULFATE) INJECTION PARENTERAL 5 mg/1mL 20 mL · فرآورده تزریقی فومپیزول (معادل سولفات) ۵ میلیگرم / ۱ میلیلیتر ۲۰ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Fomepizole · How SuppliedFDA Fomepizole · Dosage and AdministrationFDA Fomepizole · Pediatric UseFDA Fomepizole · ContraindicationsFDA Fomepizole · Pregnancy:FDA Fomepizole · Nursing Mothers:FDA Fomepizole · Pediatric Use:FDA Fomepizole · Geriatric Use:FDA Fomepizole · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1957/Fomepizole
- Clinical review⚠ Unverified