Fomepizole

فومپیزول

⚠ Unverified

🧪 VariousAlcohol dehydrogenase inhibitor (antidote)

Market / country: 🇺🇸 USA

Antizol (US)

🧮 Dose calculator

Methanol or ethylene glycol poisoning · Regimen source: FDA Fomepizole · Dosage and Administration

  • • First dose 15 mg/kg; then 10 mg/kg every 12 h for 4 doses; then 15 mg/kg every 12 h until methanol or ethylene glycol is undetectable or <20 mg/dL, the patient is asymptomatic and pH normal. Each dose over 30 min. Every 4 h during haemodialysis. Do not use polycarbonate syringes. Safety in children not established. FDA Fomepizole · Dosage and AdministrationFDA Fomepizole · Pediatric Use

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🛡️ Safety & information

Contraindications

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Fomepizole · Pregnancy:

    “Pregnancy Category C: Animal reproduction studies have not been conducted with fomepizole.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Fomepizole · Nursing Mothers:

    “Because many drugs are excreted in human milk, caution should be exercised when fomepizole is administered to a nursing woman.”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Fomepizole · Pediatric Use:

    “Safety and effectiveness in pediatric patients have not been established.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Fomepizole · Geriatric Use:

    “Safety and effectiveness in geriatric patients have not been established.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

📚 Reference status for this drug

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