Ferric carboxymaltose
فریک کربوکسیمالتوز
🩸 Blood And Blood Forming OrgansParenteral iron
Market / country: 🇺🇸 USA
Injectafer (US)
🧮 Dose calculator
Iron-deficiency anaemia · Regimen source: FDA Injectafer · 2.2
- • Total 1,500 mg per course. Adults: alternatively a single 15 mg/kg dose up to 1,000 mg. For intolerance or poor response to oral iron. FDA Injectafer · 2.2FDA Injectafer · 1
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to Injectafer. FDA Injectafer · 4
Warnings
- • Boxed warning: severe prolonged hypophosphataemia (osteomalacia, fractures); check phosphate before a repeat course and correct prior hypophosphataemia. FDA Injectafer · Boxed WarningFDA Injectafer · 2.1
Formulations
- 50 mg iron/mL (100, 500, 750, 1000 mg vials) — injection 🇺🇸 USA FDA Injectafer · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Injectafer · 8.1
“Risk Summary Parenteral iron administration may be associated with hypersensitivity reactions [ see Warnings and Precautions ( 5.2 )], which may have serious consequences, such as fetal bradycardia ( see Clinical Considerations ).”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Injectafer · 8.2
“Risk Summary The available published data on the use of ferric carboxymaltose in lactating women demonstrate that iron is present in breast milk.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Injectafer · 8.4
“The safety and effectiveness of Injectafer for IDA in pediatric patients aged 1 year and older who have normal kidney function and have either intolerance to oral iron or have had unsatisfactory response to oral iron have been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Injectafer · 8.5
“Of the 1,775 subjects in clinical studies of Injectafer, 50% were 65 years and over, while 25% were 75 years and over.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA203565
- DailyMed (FDA label)FDA Injectafer
- MedlinePlus (NIH)Ferric Carboxymaltose Injection
- WHO ATC/DDDB03AC
- Darooyab (Iran)Ferric-Carboxymaltose
🇮🇷 Registered in Iran Darooyab · G-5550/Ferric-Carboxymaltose
Dosage forms with Iranian generic codes, per Darooyab.
- 16954 · FERRIC CARBOXYMALTOSE 500MG/10ML VIAL · ویال فریک کاربوکسیمالتوس ۵۰۰ میلیگرم / ۱۰ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Injectafer · 3FDA Injectafer · 2.2FDA Injectafer · 1FDA Injectafer · 4FDA Injectafer · Boxed WarningFDA Injectafer · 2.1FDA Injectafer · 8.1FDA Injectafer · 8.2FDA Injectafer · 8.4FDA Injectafer · 8.5FDA Injectafer · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-5550/Ferric-Carboxymaltose
- Clinical review⚠ Unverified