Doz

Epoetin alfa (erythropoietin)

اپوئتین آلفا (اریتروپویتین)

⚠ Unverified

🩸 Blood And Blood Forming OrgansErythropoiesis-stimulating agent

🤰 Pregnancy:Use with caution🤱 Breastfeeding:Use with caution👶 Children:Use with caution👴 Older adults:Use with caution 🇮🇷 Registered in Iran⛔ 1 contraindications 🇺🇸 FDA approved (BLA) BLA103234ATC B03XA01

Market / country: 🇺🇸 USA

Epogen (US)

🧮 Dose calculator

Anaemia of chronic kidney disease · Regimen source: FDA Epogen · 2.2

  • • Three times WEEKLY (not daily), IV or SC (IV on haemodialysis). Lowest dose that reduces transfusion need; do not target Hb above 11. Weekly Hb until stable. FDA Epogen · 2.2
  • • Iranian syringes (Darooyab) such as 2,000, 4,000 or 10,000 units are in 0.5 mL, not 1 mL; compute the volume from the units and that syringe’s strength. Darooyab · G-1393/Recombinant-Erythropoietin

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🛡️ Safety & information

Contraindications

  • ⛔ Uncontrolled hypertension; pure red cell aplasia after an erythropoietin; serious allergy; multiple-dose vials (benzyl alcohol) in neonates, infants, pregnancy and lactation. FDA Epogen · 4

Warnings

  • • Boxed warning: ESAs increase the risk of death, MI, stroke, thrombosis and tumour progression; do not target Hb above 11 g/dL. FDA Epogen · Boxed Warning

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label: only the multiple-dose vial (benzyl alcohol) is contraindicated in pregnancy and lactation; use single-dose vials. FDA Epogen · 4

    “… actions to Epogen [see Warnings and Precautions ( 5.7 )] Epogen from multiple-dose vials contains benzyl alcohol and is contraindicated in: Neonates, infants, pregnant women, and lactating women [see Warnings and Precautions ( 5.9 ), Use in Specific Populations ( 8.1 , 8.2 , 8.4 )] .”
  • 🤱 BreastfeedingUse with caution

    Label: only the multiple-dose vial (benzyl alcohol) is contraindicated in pregnancy and lactation; use single-dose vials. FDA Epogen · 4

    “… actions to Epogen [see Warnings and Precautions ( 5.7 )] Epogen from multiple-dose vials contains benzyl alcohol and is contraindicated in: Neonates, infants, pregnant women, and lactating women [see Warnings and Precautions ( 5.9 ), Use in Specific Populations ( 8.1 , 8.2 , 8.4 )] .”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Epogen · 8.4

    “Pediatric Patients with CKD Epogen is indicated in pediatric patients, ages 1 month to 16 years of age, for the treatment of anemia associated with CKD requiring dialysis.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Epogen · 8.5

    “Dose selection and adjustment for an elderly patient should be individualized to achieve and maintain the target hemoglobin [see Dosage and Administration ( 2 )] .”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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