Emtricitabine + tenofovir DF (PrEP)
امتریسیتابین + تنوفوویر (PrEP)
🦠 Antiinfectives For Systemic UseAntiretroviral
Market / country: 🇺🇸 USA
Truvada (US)
🧮 Dose calculator
HIV pre-exposure prophylaxis (PrEP) · Regimen source: FDA Truvada · 2.5
- • Shown as the emtricitabine component (one 200/300 tablet). Confirm HIV-negative immediately before starting and at least every 3 months. FDA Truvada · 2.5FDA Truvada · Boxed Warning
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Contraindicated for PrEP with unknown or positive HIV-1 status. FDA Truvada · 4
Warnings
- • Boxed warning: hepatitis B flare after stopping; HIV drug resistance if acute infection is missed. FDA Truvada · Boxed Warning
Formulations
- Emtricitabine 200 mg + tenofovir DF 300 mg tablet — tablet 🇺🇸 USA FDA Truvada · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label: observational data have shown no increased risk of major birth defects. FDA Truvada · 8.1
“Data on the use of TRUVADA during pregnancy from observational studies have shown no increased risk of major birth defects.”
- 🤱 BreastfeedingDangerous / avoid
Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Truvada · 8.2
“Women should not breastfeed if acute HIV-1 infection is suspected because of the risk of HIV-1 transmission to the infant.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Truvada · 8.4
“Safety and effectiveness of Truvada for HIV-1 PrEP in pediatric patients weighing less than 35 kg have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Truvada · 8.5
“Clinical trials of FTC, TDF, or TRUVADA did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA021752
- DailyMed (FDA label)FDA Truvada
- MedlinePlus (NIH)Emtricitabine
- WHO ATC/DDDJ05AR03
- Darooyab (Iran)Emtricitabine-Tenofovir
🇮🇷 Registered in Iran Darooyab · G-4726/Emtricitabine-Tenofovir
Dosage forms with Iranian generic codes, per Darooyab.
- 21940 · EMTRICITABINE 200 MG + TENOFOVIR 300MG TAB · قرص امتریسیتابین ۲۰۰ میلیگرم + تنوفوویر ۳۰۰ میلیگرم
- 11460 · TENOFOVIR/EMTRICITABINE 245/200MG TAB · قرص تنوفوویر / امتریسیتابین ۲۴۵ / ۲۰۰ میلیگرم
- 51977 · EMTRICITABINE / TENOFOVIR ALAFENAMIDE (AS FUMARATE) TABLET ORAL 200 mg/25 mg · قرص امتریسیتابین / تنوفوویر آلافنامید (معادل فومارات) ۲۰۰ میلیگرم / ۲۵ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Truvada · 3FDA Truvada · 2.5FDA Truvada · Boxed WarningFDA Truvada · 4FDA Truvada · 8.1FDA Truvada · 8.2FDA Truvada · 8.4FDA Truvada · 8.5FDA Truvada · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-4726/Emtricitabine-Tenofovir
- Clinical review⚠ Unverified