Emicizumab

🧮 Dose calculator

Haemophilia A · Regimen source: FDA Hemlibra · 2.1

• • Stop prophylactic bypassing agents the day before starting; prophylactic factor VIII may continue in week 1. FDA Hemlibra · 2.1

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Hemlibra · 8.1

  “Risk Summary There are no available data on HEMLIBRA use in pregnant women to inform a drug-associated risk of major birth defects and miscarriage.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Hemlibra · 8.2

  “Risk Summary There is no information regarding the presence of emicizumab-kxwh in human milk, the effects on the breastfed child, or the effects on milk production.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Hemlibra · 8.4

  “The safety and efficacy of HEMLIBRA have been established in pediatric patients.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Hemlibra · 8.5

  “Clinical studies of HEMLIBRA did not include a sufficient number of patients aged 65 and over to determine whether they respond differently from younger patients.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Hemlibra · 8.3

  “Contraception Women of childbearing potential should use contraception while receiving HEMLIBRA.”