Dutasteride

دوتاستراید

⚠ Unverified

🚻 Genito Urinary System And Sex Hormones5-alpha-reductase inhibitor

Market / country: 🇺🇸 USA

Avodart (US)

🧮 Dose calculator

Benign prostatic hyperplasia (BPH) · Regimen source: FDA Avodart · 2.1FDA Avodart · 2.2

  • • Do not open or chew (oropharyngeal irritation). Pregnant women or those who may become pregnant must not handle capsules (skin absorption). FDA Avodart · 2FDA Avodart · 16

Enter age (weight is optional for this regimen).

🛡️ Safety & information

Contraindications

  • ⛔ Pregnancy; clinically significant hypersensitivity to dutasteride or other 5-alpha-reductase inhibitors. FDA Avodart · 4

Warnings

  • • Lowers PSA by about 50%; evaluate any confirmed PSA rise. May increase high-grade prostate cancer. Do not donate blood until 6 months after the last dose. FDA Avodart · 5

Formulations

👥 Special populations

  • 🤰 PregnancyContraindicated

    Label: contraindicated in pregnancy. FDA Avodart · 4

    “AVODART is contraindicated for use in: • Pregnancy.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Avodart · 8.2

    “Risk Summary AVODART is not indicated for use in women.”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Avodart · 8.4

    “Safety and effectiveness in pediatric patients have not been established.”
  • 👴 Older adultsNo specific problem stated

    Label: no specific difference or dose adjustment stated for older adults. FDA Avodart · 8.5

    “No overall differences in safety or efficacy were observed between these subjects and younger subjects.”
  • ⚥ Females & males of reproductive potentialUse with caution

    Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Avodart · 8.3

    “Infertility Males: The effects of dutasteride 0.5 mg/day on semen characteristics were evaluated in normal volunteers aged 18 to 52 years (n = 27 dutasteride, n = 23 placebo) throughout 52 weeks of treatment and 24 weeks of post-treatment follow-up.”

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