Dobutamine
دوبوتامین
❤️ Cardiovascular SystemInotrope (beta-1 agonist)
Market / country: 🇺🇸 USA
Dobutrex (US)
🧮 Dose calculator
Shock (septic, cardiogenic, acute hypotension) — ICU · Regimen source: FDA Dobutamine · Dosage and Administration — Recommended Dosage
- • Rarely up to 40 mcg/kg/min. The 12.5 mg/mL vial must be diluted to at least 50 mL; not with bicarbonate or alkaline solutions. FDA Dobutamine · Dosage and Administration — Recommended DosageFDA Dobutamine · Dosage and Administration
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Idiopathic hypertrophic subaortic stenosis; hypersensitivity. FDA Dobutamine · Contraindications
Formulations
- Diluted to 250 mcg/mL (label Table 1) — injection 🇺🇸 USA FDA Dobutamine · Dosage and Administration — Table 1
- Diluted to 500 mcg/mL (label Table 1) — injection 🇺🇸 USA FDA Dobutamine · Dosage and Administration — Table 1
- Diluted to 1000 mcg/mL (label Table 1) — injection 🇺🇸 USA FDA Dobutamine · Dosage and Administration — Table 1
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Dobutamine · Precautions/Warnings – Pregnancy
“Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Dobutamine · Precautions/Warnings – Nursing Mothers
“Because many drugs are excreted in human milk, caution should be exercised when dobutamine hydrochloride is administered to a nursing woman.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Dobutamine · Precautions/Warnings – Pediatric Use
“– The safety and effectiveness of Dobutamine Injection, USP for use in pediatric patients have not been studied.”
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA074086
- DailyMed (FDA label)FDA Dobutamine
- MedlinePlus (NIH)Dobutamine Injection
- WHO ATC/DDDC01CA07
- Darooyab (Iran)Dobutamine
🇮🇷 Registered in Iran Darooyab · G-1648/Dobutamine
Dosage forms with Iranian generic codes, per Darooyab.
- 20686 · DOBUTAMINE 250MG/20ML INJ · فرآورده تزریقی دوبوتامین ۲۵۰ میلیگرم / ۲۰ میلیلیتر
- 12984 · DOBUTAMINE 250MG/5ML AMP · آمپول دوبوتامین ۲۵۰ میلیگرم / ۵ میلیلیتر
- 00466 · DOBUTAMINE HCL 250MG INJ · فرآورده تزریقی دوبوتامین هیدروکلراید ۲۵۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Dobutamine · Dosage and Administration — Table 1FDA Dobutamine · Dosage and Administration — Recommended DosageFDA Dobutamine · Dosage and AdministrationFDA Dobutamine · ContraindicationsFDA Dobutamine · SPL approval / marketing categoryFDA Dobutamine · Precautions/Warnings – PregnancyFDA Dobutamine · Precautions/Warnings – Nursing MothersFDA Dobutamine · Precautions/Warnings – Pediatric Use
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1648/Dobutamine
- Clinical review⚠ Unverified