Dimethyl fumarate

🧮 Dose calculator

Multiple sclerosis (relapsing) · Regimen source: FDA Tecfidera · 2.1

• • Swallow whole. Flushing: take with food or non-enteric-coated aspirin up to 325 mg 30 min before. CBC with lymphocytes and liver tests before starting. FDA Tecfidera · 2.1FDA Tecfidera · 2.2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Tecfidera · 8.1

  “Risk Summary Available data from the TECFIDERA Pregnancy Registry, observational studies, and pharmacovigilance with dimethyl fumarate use in pregnant women have not indicated an increased risk of major birth defects, miscarriage, or other adverse maternal or fetal outcomes.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Tecfidera · 8.2

  “Risk Summary There are no data on the presence of DMF or MMF in human milk.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Tecfidera · 8.4

  “Safety and effectiveness in pediatric patients have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Tecfidera · 8.5

  “Clinical studies of TECFIDERA did not include sufficient numbers of patients aged 65 and over to determine whether they respond differently from younger patients.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.