Dexmedetomidine

🧮 Dose calculator

ICU and procedural sedation · Regimen source: FDA Precedex · 2.2, Table 1

• • Patients switched from another sedative may not need a load. Less invasive procedures (e.g. eye): 0.5 mcg/kg. Elderly and hepatic impairment: consider reduction. FDA Precedex · 2.2, Table 1

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Precedex · 8.1

  “Risk Summary Available data from published randomized controlled trials and case reports over several decades of use with intravenously administered dexmedetomidine during pregnancy have not identified a drug-associated risk of major birth defects and miscarriage; however, the reported exposures occurred after the …”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Precedex · 8.2

  “Risk Summary Available published literature reports the presence of dexmedetomidine in human milk following intravenous administration (see Data ) .”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Precedex · 8.4

  “Sedation for Non-Invasive Procedures The safety and efficacy of PRECEDEX have been established in pediatric patients 1 month to less than 18 years of age for sedation during non-invasive procedures.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Precedex · 8.5

  “In patients greater than 65 years of age, a higher incidence of bradycardia and hypotension was observed following administration of PRECEDEX [see Warnings and Precautions (5.2) ] .”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.