Deferasirox

🧮 Dose calculator

Iron overload (thalassaemia and chronic transfusion) · Regimen source: FDA Jadenu · 2.1

• • Only after ≥100 mL/kg packed RBC and ferritin consistently >1,000. Empty stomach or light meal; not with aluminium antacids. Round to the nearest whole tablet. Monthly ferritin; adjust every 3–6 months. eGFR 40–60: reduce dose. FDA Jadenu · 2.1FDA Jadenu · 2.3

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Jadenu · 8.1

  “Risk Summary There are no studies with the use of JADENU in pregnant women to inform drug-associated risks.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Jadenu · 8.2

  “Risk Summary No data are available regarding the presence of JADENU or its metabolites in human milk, the effects of the drug on the breastfed child, or the effects of the drug on milk production.”

• 👶 ChildrenUse with caution

  Label: approved from 2 years; contraindicated with eGFR <40 at any age; adjust for the child’s changing weight. FDA Jadenu · Boxed Warning

  “JADENU is contraindicated in adult and pediatric patients with eGFR less than 40 mL/min/1.73 m 2 .”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Jadenu · 8.5

  “Dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Jadenu · 8.3

  “Contraception Counsel patients to use non-hormonal method(s) of contraception since JADENU can render hormonal contraceptives ineffective [see Drug Interactions (7.2)] .”