Daunorubicin

🧮 Dose calculator

Acute myeloid leukaemia (AML) · Regimen source: FDA Daunorubicin · Dosage and Administration

• • Only under an oncologist in an equipped centre. Calculator = label mg/m² × BSA (Mosteller); protocol, cycle interval and adjustment for CBC and renal/hepatic function rest with the oncology team. FDA Daunorubicin · Dosage and Administration

Enter age and weight.

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Daunorubicin · Pregnancy

  “Daunorubicin hydrochloride may cause fetal harm when administered to a pregnant woman.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Daunorubicin · Nursing Mothers

  “Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from daunorubicin, mothers should be advised to discontinue nursing during daunorubicin therapy.”

• 👶 ChildrenUse with caution

  Label: children have lower cumulative limits (300 mg/m² over 2 years, 10 mg/kg under 2) — cardiotoxicity. FDA Daunorubicin · Warnings

  “The incidence of myocardial toxicity increases after a total cumulative dose exceeding 400 to 550 mg/m 2 in adults, 300 mg/m 2 in children more than 2 years of age, or 10 mg/kg in children less than 2 years of age.”

• 👴 Older adultsNo data

  The source for this drug has no section for this group.

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.