Conjugated estrogens

استروژن کونژوگه (پرمارین)

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🚻 Genito Urinary System And Sex HormonesOestrogen

Market / country: 🇺🇸 USA

Premarin (US)

🧮 Dose calculator

Menopausal vasomotor symptoms · Regimen source: FDA Premarin · 2.1

Enter age (weight is optional for this regimen).

🛡️ Safety & information

Contraindications

  • ⛔ Undiagnosed genital bleeding; breast or oestrogen-dependent cancer; DVT/PE or arterial thrombosis; liver disease; pregnancy. FDA Premarin · 4

Warnings

  • • Boxed warning: endometrial cancer (unopposed oestrogen with a uterus), cardiovascular disorders, breast cancer and probable dementia; lowest dose, shortest time. FDA Premarin · Boxed Warning

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Premarin · 8.1

    “Risk Summary PREMARIN is not indicated for use during pregnancy.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Premarin · 8.2

    “Risk Summary Estrogens and progestins and metabolites are present in human milk.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Premarin · 8.4

    “Estrogen therapy has been used for the induction of puberty in adolescents with some forms of pubertal delay.”
  • 👴 Older adultsDangerous / avoid

    Label: serious warning or avoid in older adults. FDA Premarin · Boxed Warning

    “WARNING: ENDOMETRIAL CANCER, CARDIOVASCULAR DISORDERS, BREAST CANCER and PROBABLE DEMENTIA See full prescribing information for complete boxed warning.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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