Conjugated estrogens
استروژن کونژوگه (پرمارین)
🚻 Genito Urinary System And Sex HormonesOestrogen
Market / country: 🇺🇸 USA
Premarin (US)
🧮 Dose calculator
Menopausal vasomotor symptoms · Regimen source: FDA Premarin · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Undiagnosed genital bleeding; breast or oestrogen-dependent cancer; DVT/PE or arterial thrombosis; liver disease; pregnancy. FDA Premarin · 4
Warnings
- • Boxed warning: endometrial cancer (unopposed oestrogen with a uterus), cardiovascular disorders, breast cancer and probable dementia; lowest dose, shortest time. FDA Premarin · Boxed Warning
Formulations
- 0.3 mg tablet — tablet 🇺🇸 USA FDA Premarin · 3
- 0.45 mg tablet — tablet 🇺🇸 USA FDA Premarin · 3
- 0.625 mg tablet — tablet 🇺🇸 USA FDA Premarin · 3
- 0.9 mg tablet — tablet 🇺🇸 USA FDA Premarin · 3
- 1.25 mg tablet — tablet 🇺🇸 USA FDA Premarin · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Premarin · 8.1
“Risk Summary PREMARIN is not indicated for use during pregnancy.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Premarin · 8.2
“Risk Summary Estrogens and progestins and metabolites are present in human milk.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Premarin · 8.4
“Estrogen therapy has been used for the induction of puberty in adolescents with some forms of pubertal delay.”
- 👴 Older adultsDangerous / avoid
Label: serious warning or avoid in older adults. FDA Premarin · Boxed Warning
“WARNING: ENDOMETRIAL CANCER, CARDIOVASCULAR DISORDERS, BREAST CANCER and PROBABLE DEMENTIA See full prescribing information for complete boxed warning.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA004782
- DailyMed (FDA label)FDA Premarin
- MedlinePlus (NIH)EstrogenEstrogen Injection
- WHO ATC/DDDG03CA57
- Darooyab (Iran)Conjugated-Estrogens
🇮🇷 Registered in Iran Darooyab · G-3237/Conjugated-Estrogens
Dosage forms with Iranian generic codes, per Darooyab.
- 00352 · CONJUGATED ESTROGENS 0.625MG TAB · قرص کونژوگه استروژنها ۰٫۶۲۵ میلیگرم
- 00353 · CONJUGATED ESTROGENS 0.625MG/G 42.5G VAG CREAM · کرم واژینال کونژوگه استروژنها ۰٫۶۲۵ میلیگرم / گرم ۴۲٫۵ گرم
- 00354 · CONJUGATED ESTROGENS 1.25MG TAB · قرص کونژوگه استروژنها ۱٫۲۵ میلیگرم
- 00355 · CONJUGATED ESTROGENS 25MG/5ML VIAL · ویال کونژوگه استروژنها ۲۵ میلیگرم / ۵ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Premarin · 3FDA Premarin · 2.1FDA Premarin · 4FDA Premarin · Boxed WarningFDA Premarin · 8.1FDA Premarin · 8.2FDA Premarin · 8.4FDA Premarin · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-3237/Conjugated-Estrogens
- Clinical review⚠ Unverified