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Clozapine
کلوزاپین
🧠 PsychiatryAtypical antipsychotic
Market / country: 🇺🇸 USA
Clozaril (US)
🧮 Dose calculator
Schizophrenia · Regimen source: FDA Clozapine · 2.2FDA Clozapine · 2
- • Increase by 25–50 mg/day to target 150–225 mg twice daily; max 450 mg twice daily. Neutrophil monitoring required. FDA Clozapine · 2FDA Clozapine · 2.2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to clozapine. FDA Clozapine · 4
- ⚠️ Boxed warning: severe neutropenia, orthostatic hypotension and syncope, seizures, myocarditis, mortality in elderly dementia patients. FDA Clozapine · Boxed Warning
- ⛔ Not established in children. FDA Clozapine · 8.4
Formulations
- 25 mg tablet (scored) — tablet 🇺🇸 USA FDA Clozapine · 3
- 100 mg tablet (scored) — tablet 🇺🇸 USA FDA Clozapine · 3
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Clozapine · 3FDA Clozapine · 2.2FDA Clozapine · 2FDA Clozapine · 4FDA Clozapine · Boxed WarningFDA Clozapine · 8.4
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Clinical review⚠ Unverified