Clindamycin vaginal cream

🧮 Dose calculator

Bacterial vaginosis · Regimen source: FDA Clindesse · 2FDA Clindesse · 1

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Clindesse · 8.1

  “Risk Summary Clindesse has not been studied in pregnant women.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Clindesse · 8.2

  “Risk Summary The systemic exposure (based on AUC and C max ) of Clindesse is substantially lower than intravenous administration of clindamycin [see Clinical Pharmacology ( 12.3 )] ; therefore, adverse effects on the breastfed infant are not expected from transfer of clindamycin into breastmilk.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Clindesse · 8.4

  “The safety and efficacy of Clindesse in the treatment of bacterial vaginosis in post-menarchal females have been established on the extrapolation of clinical trial data from adult women.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Clindesse · 8.5

  “Clinical studies with Clindesse did not include sufficient numbers of subjects 65 years of age or older to determine whether they respond differently than younger subjects.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Clindesse · 8.3

  “Contraception Clindesse contains mineral oil that may weaken latex or rubber products such as condoms or vaginal contraceptive diaphragms.”