Bupivacaine

بوپیواکائین (مارکائین)

⚠ Unverified

🧠 Nervous SystemLong-acting amide local anaesthetic

Market / country: 🇺🇸 USA

Marcaine / Sensorcaine (US)

🧮 Dose calculator

Spinal and epidural anaesthesia · Regimen source: FDA Marcaine Spinal · 2.2

  • • Smallest effective dose and concentration. Only by experienced clinicians with resuscitation available. FDA Marcaine Spinal · 2.2

Enter age (weight is optional for this regimen).

🛡️ Safety & information

Contraindications

  • ⛔ Obstetric paracervical block (fetal bradycardia and death); IV regional anaesthesia (Bier block); hypersensitivity to amide local anaesthetics. Spinal: septicaemia, severe haemorrhage, shock, significant arrhythmia, local infection. FDA Marcaine · 4FDA Marcaine Spinal · 4

Warnings

  • • Systemic toxicity (seizures, cardiac arrest) with intravascular injection; have resuscitation ready. FDA Marcaine · 5

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Marcaine Spinal · 8.1

    “Risk Summary The available data on the use of MARCAINE SPINAL in pregnant women do not establish the presence or absence of developmental toxicity related to the use of MARCAINE SPINAL.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Marcaine Spinal · 8.2

    “Risk Summary Lactation studies have not been conducted with bupivacaine.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Marcaine Spinal · 8.4

    “MARCAINE SPINAL is approved for use in adults only.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Marcaine Spinal · 8.5

    “Patients 65 years and over, particularly those with hypertension, may be at increased risk for developing hypotension while undergoing spinal anesthesia with MARCAINE SPINAL.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

📚 Reference status for this drug

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