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Allopurinol
آلوپورینول
🦴 Musculo-Skeletal SystemXanthine oxidase inhibitor
🤰 Pregnancy:Dangerous / avoid🤱 Breastfeeding:Dangerous / avoid👶 Children:Use with caution 🇮🇷 Registered in Iran⛔ 1 contraindications 🇺🇸 FDA approved generic (ANDA) ANDA204467ATC M04AA01
Market / country: 🇺🇸 USA
Zyloprim (US)
🧮 Dose calculator
Gout · Regimen source: FDA Allopurinol · 2.3
- • Increase by 100 mg weekly until uric acid ≤6 mg/dL; max 800 mg/day. Renal impairment: start 50 mg. Treat flares alongside. FDA Allopurinol · 2.3FDA Allopurinol · 2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ History of hypersensitivity reaction to allopurinol. FDA Allopurinol · 4
Formulations
- 100 mg tablet (scored) — tablet 🇺🇸 USA FDA Allopurinol · 3
- 200 mg tablet (scored) — tablet 🇺🇸 USA FDA Allopurinol · 3
- 300 mg tablet (scored) — tablet 🇺🇸 USA FDA Allopurinol · 3
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Allopurinol · 8.1
“Risk Summary Based on findings in animals, allopurinol tablets may cause fetal harm when administered to a pregnant woman.”
- 🤱 BreastfeedingDangerous / avoid
Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Allopurinol · 8.2
“Because of the potential for serious adverse reactions in a breastfed child, advise women not to breastfeed during treatments with allopurinol tablets and for one week after the last dose.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Allopurinol · 8.4
“Hyperuricemia Associated with Cancer Therapy The safety and effectiveness of allopurinol for the management of pediatric patients with leukemia, lymphoma and solid tumor malignancies who are receiving cancer therapy which causes elevations of serum and urinary uric acid levels have been established in approximately …”
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA204467
- DailyMed (FDA label)FDA Allopurinol
- MedlinePlus (NIH)AllopurinolAllopurinol Injection
- WHO ATC/DDDM04AA01
- Darooyab (Iran)Allopurinol
🇮🇷 Registered in Iran Darooyab · G-754/Allopurinol
Dosage forms with Iranian generic codes, per Darooyab.
- 00038 · ALLOPURINOL 100MG TAB · قرص آلوپورینول ۱۰۰ میلیگرم
- 02017 · ALLOPURINOL 300MG TAB · قرص آلوپورینول ۳۰۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Allopurinol · 3FDA Allopurinol · 2.3FDA Allopurinol · 2FDA Allopurinol · 2.5FDA Allopurinol · 2.4FDA Allopurinol · 4FDA Allopurinol · 8.1FDA Allopurinol · 8.2FDA Allopurinol · 8.4FDA Allopurinol · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-754/Allopurinol
- Clinical review⚠ Unverified