[{"data":1,"prerenderedAt":208},["ShallowReactive",2],{"drug-vardenafil":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":59,"contraindications":88,"warnings":108,"renal":109,"monitoring":110,"interactions":111,"review":118,"examples":121,"atc":127,"iran":129,"links":153,"populations":170,"usApproval":203},"vardenafil",1,{"fa":7,"en":8},"واردنافیل","Vardenafil","genitourinary-sex-hormones",{"fa":11,"en":12},"مهارکننده PDE5","PDE5 inhibitor",[14],{"name":15,"market":16},"Levitra","US",[18,19,7],"levitra","لویترا",[21,35,43,51],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-2-5","tablet","oral","2.5 mg tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},2.5,"mg",false,[16],[32],{"source":33,"section":34},"fda-vardenafil","3",{"id":36,"form":23,"route":24,"label":37,"concentration":38,"markets":40,"refs":41},"tab-5","5 mg tablet",{"amount":39,"unit":28,"perUnit":23,"scored":29},5,[16],[42],{"source":33,"section":34},{"id":44,"form":23,"route":24,"label":45,"concentration":46,"markets":48,"refs":49},"tab-10","10 mg tablet",{"amount":47,"unit":28,"perUnit":23,"scored":29},10,[16],[50],{"source":33,"section":34},{"id":52,"form":23,"route":24,"label":53,"concentration":54,"markets":56,"refs":57},"tab-20","20 mg tablet",{"amount":55,"unit":28,"perUnit":23,"scored":29},20,[16],[58],{"source":33,"section":34},[60],{"id":61,"disease":62,"label":63,"population":66,"type":70,"unit":28,"dose":71,"refs":72,"limits":75,"notes":79},"ed","erectile-dysfunction",{"fa":64,"en":65},"اختلال نعوذ — ۱۰ mg حدود ۶۰ دقیقه پیش از فعالیت جنسی، حداکثر یک بار در روز","Erectile dysfunction — 10 mg about 60 min before sexual activity, max once daily",{"minAge":67},{"value":68,"unit":69},18,"year","fixed",{"perDose":47,"dosesPerDay":5},[73],{"source":33,"section":74},"2.1",{"maxPerDay":55,"refs":76},[77],{"source":33,"section":78},"2",[80],{"text":81,"refs":84},{"fa":82,"en":83},"بسته به اثر و تحمل ۵ تا ۲۰ mg. ۶۵ سال به بالا: شروع ۵ mg.","Adjust to 5–20 mg by effect and tolerability. ≥65 y: start 5 mg.",[85,86],{"source":33,"section":78},{"source":33,"section":87},"2.3",[89,98],{"id":90,"severity":91,"text":92,"refs":95},"nitrates","block",{"fa":93,"en":94},"مصرف هم‌زمان با نیترات‌ها (مثل نیتروگلیسرین) یا ریوسیگوات — افت فشار شدید.","Use with nitrates (e.g. nitroglycerin) or riociguat — severe hypotension.",[96],{"source":33,"section":97},"4",{"id":99,"severity":91,"rule":100,"text":102,"refs":105},"child",{"maxAge":101},{"value":68,"unit":69},{"fa":103,"en":104},"برای کودکان اندیکاسیون ندارد.","Not indicated in children.",[106],{"source":33,"section":107},"8.4",[],[],[],[112],{"with":90,"text":113,"refs":116},{"fa":114,"en":115},"با نیترات‌ها منع مصرف.","Contraindicated with nitrates.",[117],{"source":33,"section":97},{"status":119,"reviewer":120,"date":120},"unverified",null,[122],{"regimen":61,"formulation":44,"input":123,"expect":126},{"ageYears":124,"weightKg":125},50,80,{"perDose":47,"tabletsPerDoseRounded":5},[128],"G04BE09",{"status":130,"forms":131,"refs":148},"registered",[132,136,140,144],{"code":133,"en":134,"fa":135},"08831","VARDENAFIL 10MG TAB","قرص واردنافیل ۱۰ میلی‌گرم",{"code":137,"en":138,"fa":139},"09293","VARDENAFIL 20MG TAB","قرص واردنافیل ۲۰ میلی‌گرم",{"code":141,"en":142,"fa":143},"13263","VARDENAFIL 5MG  TAB","قرص واردنافیل ۵ میلی‌گرم",{"code":145,"en":146,"fa":147},"18016","VERDENAFIL 10MG  TAB.","قرص وردنافیل ۱۰ میلی‌گرم .",[149],{"source":150,"section":151,"url":152},"darooyab-generic","G-4344\u002FVardenafil","https:\u002F\u002Fwww.darooyab.ir\u002FG-4344\u002FVardenafil",[154,158,162,165,168],{"kind":155,"url":156,"label":157},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=209057","ANDA209057",{"kind":159,"url":160,"label":161},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=2782efed-6198-47b9-81ac-3e255e2ab7f6","FDA Vardenafil",{"kind":163,"url":164,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa603035.html",{"kind":166,"url":167,"label":128},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=G04BE09",{"kind":169,"url":152,"label":8},"darooyab",{"pregnancy":171,"lactation":180,"pediatric":187,"geriatric":195},{"level":172,"text":173,"quote":176,"refs":177},"caution",{"fa":174,"en":175},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Vardenafil hydrochloride tablets are not indicated for use in females.",[178],{"source":33,"section":179},"8.1",{"level":172,"text":181,"quote":176,"refs":184},{"fa":182,"en":183},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.",[185],{"source":33,"section":186},"8.2",{"level":188,"text":189,"quote":192,"refs":193},"not-established",{"fa":190,"en":191},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Vardenafil hydrochloride tablets are not indicated for use in pediatric patients.",[194],{"source":33,"section":107},{"level":172,"text":196,"quote":199,"refs":200},{"fa":197,"en":198},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Elderly males 65 years of age and older have higher vardenafil plasma concentrations than younger males (18 – 45 years), mean C max and AUC were 34% and 52% higher, respectively.",[201],{"source":33,"section":202},"8.5",{"kind":204,"refs":205,"id":157},"ANDA",[206],{"source":33,"section":207},"SPL approval \u002F marketing category",1792091070116]