[{"data":1,"prerenderedAt":154},["ShallowReactive",2],{"drug-triclabendazole":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":35,"contraindications":61,"warnings":71,"renal":72,"monitoring":73,"interactions":74,"review":75,"examples":78,"atc":84,"iran":86,"links":98,"populations":115,"usApproval":149},"triclabendazole",1,{"fa":7,"en":8},"تریکلابندازول","Triclabendazole","antiparasitic",{"fa":11,"en":12},"ضدکرم (بنزیمیدازول)","Anthelmintic (benzimidazole)",[14],{"name":15,"market":16},"Egaten","US",[18,19,7],"egaten","اگاتن",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-250","tablet","oral","250 mg tablet (scored)",{"amount":27,"unit":28,"perUnit":23,"scored":29},250,"mg",true,[16],[32],{"source":33,"section":34},"fda-egaten","3",[36],{"id":37,"disease":38,"label":39,"population":42,"type":46,"unit":28,"dose":47,"refs":50,"durationDays":53,"notes":54},"fasc","fascioliasis",{"fa":40,"en":41},"فاسیولیازیس — ۱۰ mg\u002Fkg دو نوبت با فاصله ۱۲ ساعت (۶ سال به بالا)","Fascioliasis — 10 mg\u002Fkg twice, 12 h apart (≥6 y)",{"minAge":43},{"value":44,"unit":45},6,"year","weightBased",{"perKgPerDose":48,"intervalHours":49},10,12,[51],{"source":33,"section":52},"2",{"min":5,"max":5},[55],{"text":56,"refs":59},{"fa":57,"en":58},"فقط ۲ نوبت. همراه غذا. برچسب: اگر دوز دقیق ممکن نیست، به سمت بالا گرد شود (نیم قرص = ۱۲۵ mg).","Two doses only. With food. Label: if the dose cannot be matched exactly, round up (half tablet = 125 mg).",[60],{"source":33,"section":52},[62],{"id":63,"severity":64,"text":65,"refs":68},"hyper","block",{"fa":66,"en":67},"حساسیت به تریکلابندازول یا سایر بنزیمیدازول‌ها.","Hypersensitivity to triclabendazole or other benzimidazoles.",[69],{"source":33,"section":70},"4",[],[],[],[],{"status":76,"reviewer":77,"date":77},"unverified",null,[79],{"regimen":37,"formulation":22,"input":80,"expect":83},{"ageYears":81,"weightKg":82},8,25,{"perDose":27,"tabletsPerDoseRounded":5},[85],"P02BX04",{"status":87,"forms":88,"refs":93},"registered",[89],{"code":90,"en":91,"fa":92},"01697","TRICLABENDAZOLE 250MG TAB","قرص تریکلابندازول ۲۵۰ میلی‌گرم",[94],{"source":95,"section":96,"url":97},"darooyab-generic","G-270\u002FTriclabendazole","https:\u002F\u002Fwww.darooyab.ir\u002FG-270\u002FTriclabendazole",[99,103,107,110,113],{"kind":100,"url":101,"label":102},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=208711","NDA208711",{"kind":104,"url":105,"label":106},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=5552884e-10ea-450c-9658-d3d4f33c946e","FDA Egaten",{"kind":108,"url":109,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa619048.html",{"kind":111,"url":112,"label":85},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=P02BX04",{"kind":114,"url":97,"label":8},"darooyab",{"pregnancy":116,"lactation":125,"pediatric":133,"geriatric":141},{"level":117,"text":118,"quote":121,"refs":122},"caution",{"fa":119,"en":120},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary There are no available data on EGATEN use in pregnant women to inform a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes.",[123],{"source":33,"section":124},"8.1",{"level":117,"text":126,"quote":129,"refs":130},{"fa":127,"en":128},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There are no data on the presence of triclabendazole in human milk, the effects on the breastfed infant, or the effects on milk production.",[131],{"source":33,"section":132},"8.2",{"level":117,"text":134,"quote":137,"refs":138},{"fa":135,"en":136},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and effectiveness of EGATEN has been established in pediatric patients aged 6 years and older.",[139],{"source":33,"section":140},"8.4",{"level":117,"text":142,"quote":145,"refs":146},{"fa":143,"en":144},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","In general, dose selection for an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.",[147],{"source":33,"section":148},"8.5",{"kind":150,"refs":151,"id":102},"NDA",[152],{"source":33,"section":153},"SPL approval \u002F marketing category",1792108439524]