[{"data":1,"prerenderedAt":248},["ShallowReactive",2],{"drug-testosterone":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":19,"formulations":23,"regimens":50,"contraindications":95,"warnings":107,"renal":114,"monitoring":115,"interactions":116,"review":117,"examples":120,"atc":126,"iran":128,"links":178,"populations":201,"usApproval":243},"testosterone",1,{"fa":7,"en":8},"تستوسترون","Testosterone","genitourinary-sex-hormones",{"fa":11,"en":12},"آندروژن","Androgen",[14,17],{"name":15,"market":16},"Depo-Testosterone","US",{"name":18,"market":16},"AndroGel",[4,7,20,21,22],"تستوویرون","آمپول تستوسترون","ژل تستوسترون",[24,37],{"id":25,"form":26,"route":27,"label":28,"concentration":29,"markets":32,"refs":33},"inj-200","injection","im","Testosterone cypionate 200 mg\u002FmL (IM)",{"amount":30,"unit":31,"perVolumeMl":5},200,"mg",[16],[34],{"source":35,"section":36},"fda-testocyp","How Supplied",{"id":38,"form":39,"route":40,"label":41,"concentration":42,"markets":45,"refs":46},"gel-pump","gel","topical","AndroGel 1.62%: 20.25 mg testosterone per pump actuation",{"amount":43,"unit":31,"perUnit":44},20.25,"actuation",[16],[47],{"source":48,"section":49},"fda-androgel","3",[51,69],{"id":27,"disease":52,"label":53,"population":56,"type":60,"unit":31,"dose":61,"refs":65,"allowedFormulations":68},"male-hypogonadism",{"fa":54,"en":55},"هیپوگنادیسم مردانه — ۵۰ تا ۴۰۰ mg عضلانی هر ۲ تا ۴ هفته","Male hypogonadism — 50–400 mg IM every 2–4 weeks",{"minAge":57},{"value":58,"unit":59},18,"year","notCalculated",{"reason":62},{"fa":63,"en":64},"برچسب: ۵۰ تا ۴۰۰ mg عضلانی هر ۲ تا ۴ هفته؛ بر اساس سطح تستوسترون و پاسخ تنظیم شود.","Label: 50–400 mg IM every 2–4 weeks, adjusted to testosterone level and response.",[66],{"source":35,"section":67},"Dosage and Administration",[25],{"id":39,"disease":52,"label":70,"population":73,"type":75,"unit":31,"dose":76,"refs":78,"limits":81,"allowedFormulations":85,"notes":86},{"fa":71,"en":72},"هیپوگنادیسم مردانه — ژل ۱٫۶۲٪: ۴۰٫۵ mg (۲ پاف) صبح روی شانه و بازو","Male hypogonadism — 1.62% gel: 40.5 mg (2 pumps) each morning to shoulders\u002Fupper arms",{"minAge":74},{"value":58,"unit":59},"fixed",{"perDose":77,"dosesPerDay":5},40.5,[79],{"source":48,"section":80},"2.1",{"maxPerDay":82,"refs":83},81,[84],{"source":48,"section":80},[38],[87],{"text":88,"refs":91},{"fa":89,"en":90},"بر اساس سطح تستوسترون صبح بین ۲۰٫۲۵ و ۸۱ mg تنظیم شود. پوست کودکان و زنان با محل ژل تماس نیابد.","Adjust between 20.25 and 81 mg by morning testosterone level. Keep children and women away from application sites.",[92,93],{"source":48,"section":80},{"source":48,"section":94},"Boxed Warning",[96],{"id":97,"severity":98,"text":99,"refs":102},"ci","block",{"fa":100,"en":101},"سرطان پستان در مرد یا سرطان پروستات (شناخته‌شده یا مشکوک)؛ زنان باردار.","Male breast cancer or known\u002Fsuspected prostate cancer; pregnant women.",[103,105],{"source":48,"section":104},"4",{"source":35,"section":106},"Contraindications",[108],{"text":109,"refs":112},{"fa":110,"en":111},"هشدار جعبه‌ای ژل: انتقال ثانویه به کودکان (بلوغ زودرس) — دست‌ها شسته و محل پوشانده شود.","Gel boxed warning: secondary exposure of children (virilisation) — wash hands and cover the site.",[113],{"source":48,"section":94},[],[],[],{"status":118,"reviewer":119,"date":119},"unverified",null,[121],{"regimen":39,"formulation":38,"input":122,"expect":125},{"ageYears":123,"weightKg":124},50,80,{"perDose":77},[127],"G03BA03",{"status":129,"forms":130,"refs":173},"registered",[131,135,139,142,146,150,154,158,162,166,169],{"code":132,"en":133,"fa":134},"06605","TESTOSTERONE 50MG\u002FG SACHET","ساشه تستوسترون ۵۰ میلی‌گرم \u002F گرم",{"code":136,"en":137,"fa":138},"14737","TESTOSTERONE 5MG PATCH","پچ پوستی تستوسترون ۵ میلی‌گرم",{"code":140,"en":141,"fa":22},"05961","TESTOSTERONE GEL",{"code":143,"en":144,"fa":145},"01200","TESTOSTRONE ENANTATE 100MG\u002F1ML AMP","آمپول تستوسترون انانتات ۱۰۰ میلی‌گرم \u002F ۱ میلی‌لیتر",{"code":147,"en":148,"fa":149},"01201","TESTOSTRONE ENANTATE 250MG\u002F1ML AMP","آمپول تستوسترون انانتات ۲۵۰ میلی‌گرم \u002F ۱ میلی‌لیتر",{"code":151,"en":152,"fa":153},"01941","TESTOSTRONE UNDECANOATE 40MG CAP","کپسول تستوسترون آندکانوات ۴۰ میلی‌گرم",{"code":155,"en":156,"fa":157},"12066","TESTOSTRONE UNDECANOATE 4ML AMP","آمپول تستوسترون آندکانوات ۴ میلی‌لیتر",{"code":159,"en":160,"fa":161},"52157","TESTOSTERONE GEL TOPICAL 1 % 5 g","ژل موضعی تستوسترون ۱ درصد ۵ گرم",{"code":163,"en":164,"fa":165},"50872","TESTOSTERONE ENANTHATE INJECTION PARENTERAL 250 mg\u002F1mL","فرآورده تزریقی تستوسترون انانتات ۲۵۰ میلی‌گرم \u002F ۱ میلی‌لیتر",{"code":167,"en":168,"fa":153},"51119","TESTOSTERONE UNDECANOATE CAPSULE ORAL 40 mg",{"code":170,"en":171,"fa":172},"51918","TESTOSTERONE UNDECANOATE INJECTION, SOLUTION PARENTERAL 250 mg\u002F1mL 4 mL","محلول تزریقی تستوسترون آندکانوات ۲۵۰ میلی‌گرم \u002F ۱ میلی‌لیتر ۴ میلی‌لیتر",[174],{"source":175,"section":176,"url":177},"darooyab-generic","G-3315\u002FTestosterone","https:\u002F\u002Fwww.darooyab.ir\u002FG-3315\u002FTestosterone",[179,183,187,190,193,196,199],{"kind":180,"url":181,"label":182},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=022309","NDA022309",{"kind":184,"url":185,"label":186},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=f4e8d29b-8707-4d47-e053-2a95a90aecee","FDA AndroGel 1.62%",{"kind":184,"url":188,"label":189},"https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=375dd035-b792-4cb7-9fe6-bb367b87bdba","FDA Testosterone cyp.",{"kind":191,"url":192,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa619028.html",{"kind":191,"url":194,"label":195},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa603034.html","Testosterone Buccal",{"kind":197,"url":198,"label":127},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=G03BA03",{"kind":200,"url":177,"label":8},"darooyab",{"pregnancy":202,"lactation":210,"pediatric":219,"geriatric":227,"reproductive":235},{"level":203,"text":204,"quote":207,"refs":208},"contraindicated",{"fa":205,"en":206},"برچسب: در بارداری منع مصرف دارد.","Label: contraindicated in pregnancy.","AndroGel 1.62% is contraindicated in women who are pregnant.",[209],{"source":48,"section":104},{"level":211,"text":212,"quote":215,"refs":216},"caution",{"fa":213,"en":214},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary AndroGel 1.62% is not indicated for use in women.",[217],{"source":48,"section":218},"8.2",{"level":220,"text":221,"quote":224,"refs":225},"avoid",{"fa":222,"en":223},"هشدار جعبه‌ای برچسب درباره کودکان.","Boxed warning in the label about children.","Virilization has been reported in children who were secondarily exposed to testosterone gel [see Warnings and Precautions ( 5.1 ) and Adverse Reactions ( 6.2 )].",[226],{"source":48,"section":94},{"level":211,"text":228,"quote":231,"refs":232},{"fa":229,"en":230},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Additionally, there is insufficient long-term safety data in geriatric patients to assess the potentially increased risks of cardiovascular disease and prostate cancer.",[233],{"source":48,"section":234},"8.5",{"level":211,"text":236,"quote":239,"refs":240},{"fa":237,"en":238},"برچسب نکته‌ای درباره بارداری، پیشگیری یا باروری زنان و مردان دارد.","Label has advice on pregnancy testing, contraception or fertility for females and males.","Infertility Testis disorder, testicular atrophy, and oligospermia have been identified during use of AndroGel 1.62% [see Adverse Reactions ( 6.1 , 6.2 )] .",[241],{"source":48,"section":242},"8.3",{"kind":244,"refs":245,"id":182},"NDA",[246],{"source":48,"section":247},"SPL approval \u002F marketing category",1792091068988]