[{"data":1,"prerenderedAt":207},["ShallowReactive",2],{"drug-sulfasalazine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":35,"contraindications":105,"warnings":115,"renal":116,"monitoring":117,"interactions":118,"review":119,"examples":122,"atc":137,"iran":139,"usApproval":159,"links":165,"populations":181},"sulfasalazine",1,{"fa":7,"en":8},"سولفاسالازین","Sulfasalazine","alimentary-metabolism",{"fa":11,"en":12},"آمینوسالیسیلات \u002F DMARD","Aminosalicylate \u002F DMARD",[14],{"name":15,"market":16},"Azulfidine EN-tabs","US",[18,19,7],"azulfidine","salazopyrin",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-500","tablet","oral","500 mg delayed-release tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},500,"mg",false,[16],[32],{"source":33,"section":34},"fda-sulfasalazine","How Supplied",[36,64,86],{"id":37,"disease":38,"label":39,"population":42,"type":46,"unit":28,"dose":47,"refs":50,"limits":53,"notes":57},"uc-adult","ulcerative-colitis",{"fa":40,"en":41},"کولیت اولسروز — بزرگسال: ۳ تا ۴ g در روز در دوزهای مساوی","Ulcerative colitis — adult: 3–4 g\u002Fday in divided doses",{"minAge":43},{"value":44,"unit":45},18,"year","fixed",{"perDose":48,"dosesPerDay":49},1000,3,[51],{"source":33,"section":52},"Dosage and Administration",{"maxPerDay":54,"refs":55},4000,[56],{"source":33,"section":52},[58],{"text":59,"refs":62},{"fa":60,"en":61},"فاصله دوزها حداکثر ۸ ساعت، پس از غذا، قرص کامل. می‌توان با ۱ تا ۲ g در روز شروع کرد. نگهدارنده: ۲ g در روز.","Dose intervals ≤8 h, after meals, swallow whole. May start at 1–2 g\u002Fday. Maintenance: 2 g\u002Fday.",[63],{"source":33,"section":52},{"id":65,"disease":38,"label":66,"population":69,"type":73,"unit":28,"dose":74,"refs":77,"notes":79},"uc-child",{"fa":67,"en":68},"کولیت اولسروز — کودک ۶ سال به بالا: ۴۰ تا ۶۰ mg\u002Fkg\u002Fروز در ۳ تا ۶ دوز","Ulcerative colitis — child ≥6 y: 40–60 mg\u002Fkg\u002Fday in 3–6 doses",{"minAge":70,"maxAge":72},{"value":71,"unit":45},6,{"value":44,"unit":45},"weightBased",{"perKgPerDay":75,"perKgPerDayMax":76,"dividedDoses":49},40,60,[78],{"source":33,"section":52},[80],{"text":81,"refs":84},{"fa":82,"en":83},"نگهدارنده: ۳۰ mg\u002Fkg\u002Fروز در ۴ دوز.","Maintenance: 30 mg\u002Fkg\u002Fday in 4 doses.",[85],{"source":33,"section":52},{"id":87,"disease":88,"label":89,"population":92,"type":46,"unit":28,"dose":94,"refs":96,"notes":98},"ra","rheumatoid-arthritis",{"fa":90,"en":91},"آرتریت روماتوئید — ۲ g در روز در ۲ دوز","Rheumatoid arthritis — 2 g\u002Fday in 2 doses",{"minAge":93},{"value":44,"unit":45},{"perDose":48,"dosesPerDay":95},2,[97],{"source":33,"section":52},[99],{"text":100,"refs":103},{"fa":101,"en":102},"بهتر است با ۰٫۵ تا ۱ g در روز شروع و تدریجی افزایش. پاسخ معمولاً پس از ۴ تا ۱۲ هفته.","Start at 0.5–1 g\u002Fday and increase gradually. Response usually after 4–12 weeks.",[104],{"source":33,"section":52},[106],{"id":107,"severity":108,"text":109,"refs":112},"ci","block",{"fa":110,"en":111},"حساسیت به سولفاسالازین، سولفونامیدها یا سالیسیلات‌ها؛ انسداد روده یا ادراری؛ پورفیری.","Hypersensitivity to sulfasalazine, sulfonamides or salicylates; intestinal or urinary obstruction; porphyria.",[113],{"source":33,"section":114},"Contraindications",[],[],[],[],{"status":120,"reviewer":121,"date":121},"unverified",null,[123,127,133],{"regimen":37,"formulation":22,"input":124,"expect":126},{"ageYears":75,"weightKg":125},70,{"perDose":48,"tabletsPerDoseRounded":95},{"regimen":65,"formulation":22,"input":128,"expect":131},{"ageYears":129,"weightKg":130},15,75,{"perDose":48,"upperPerDose":132},1500,{"regimen":87,"formulation":22,"input":134,"expect":136},{"ageYears":135,"weightKg":125},50,{"perDose":48,"tabletsPerDoseRounded":95},[138],"A07EC01",{"status":140,"forms":141,"refs":154},"registered",[142,146,150],{"code":143,"en":144,"fa":145},"01184","SULFASALAZINE 3MG\u002F100ML ENEMA","انما سولفاسالازین ۳ میلی‌گرم \u002F ۱۰۰ میلی‌لیتر",{"code":147,"en":148,"fa":149},"04150","SULFASALAZINE 500MG EC TAB","قرص انتریک‌کوتد سولفاسالازین ۵۰۰ میلی‌گرم",{"code":151,"en":152,"fa":153},"01183","SULFASALAZINE 500MG TAB","قرص سولفاسالازین ۵۰۰ میلی‌گرم",[155],{"source":156,"section":157,"url":158},"darooyab-generic","G-2652\u002FSulfasalazine","https:\u002F\u002Fwww.darooyab.ir\u002FG-2652\u002FSulfasalazine",{"kind":160,"refs":161,"id":164},"NDA authorized generic",[162],{"source":33,"section":163},"SPL approval \u002F marketing category","NDA007073",[166,169,173,176,179],{"kind":167,"url":168,"label":164},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=007073",{"kind":170,"url":171,"label":172},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=257cee60-b68f-4c2b-b57d-8e4d73d17e09","FDA Sulfasalazine DR",{"kind":174,"url":175,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682204.html",{"kind":177,"url":178,"label":138},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=A07EC01",{"kind":180,"url":158,"label":8},"darooyab",{"pregnancy":182,"lactation":191,"pediatric":199},{"level":183,"text":184,"quote":187,"refs":188},"caution",{"fa":185,"en":186},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.",[189],{"source":33,"section":190},"Pregnancy:",{"level":183,"text":192,"quote":195,"refs":196},{"fa":193,"en":194},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Caution should be exercised when sulfasalazine delayed release tablets are administered to a nursing mother.",[197],{"source":33,"section":198},"Nursing Mothers:",{"level":183,"text":200,"quote":203,"refs":204},{"fa":201,"en":202},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The safety and effectiveness of sulfasalazine delayed release tablets in pediatric patients below the age of 2 years with ulcerative colitis have not been established.",[205],{"source":33,"section":206},"Pediatric Use:",1792111468786]