[{"data":1,"prerenderedAt":252},["ShallowReactive",2],{"drug-rocuronium":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":44,"contraindications":140,"warnings":150,"renal":159,"monitoring":160,"interactions":161,"review":162,"examples":165,"atc":189,"iran":191,"usApproval":207,"links":213,"populations":226},"rocuronium",1,{"fa":7,"en":8},"روکورونیوم","Rocuronium","musculoskeletal",{"fa":11,"en":12},"شل‌کننده عضلانی غیردپلاریزان","Non-depolarising neuromuscular blocker",[14],{"name":15,"market":16},"Zemuron","US",[18,19,7,20],"zemuron","esmeron","اسمرون",[22,35],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":30,"refs":31},"inj-10","injection","iv","10 mg\u002FmL (50 mg\u002F5 mL, 100 mg\u002F10 mL)",{"amount":28,"unit":29,"perVolumeMl":5},10,"mg",[16],[32],{"source":33,"section":34},"fda-rocuronium","3",{"id":36,"form":24,"route":25,"label":37,"concentration":38,"markets":41,"refs":42},"inj-10-mcg","10 mg\u002FmL = 10,000 mcg\u002FmL (for infusion rate)",{"amount":39,"unit":40,"perVolumeMl":5},10000,"mcg",[16],[43],{"source":33,"section":34},[45,80,101,121],{"id":46,"disease":47,"label":48,"population":51,"type":55,"unit":29,"dose":56,"refs":59,"durationDays":64,"allowedFormulations":65,"notes":66},"intub","intubation-nmb",{"fa":49,"en":50},"لوله‌گذاری — ۰٫۶ mg\u002Fkg (بزرگسال و کودک)","Intubation — 0.6 mg\u002Fkg (adults and children)",{"minAge":52},{"value":53,"unit":54},3,"month","weightBased",{"perKgPerDose":57,"intervalHours":58},0.6,24,[60,62],{"source":33,"section":61},"2.2",{"source":33,"section":63},"2.6",{"min":5,"max":5},[23],[67,74],{"text":68,"refs":71},{"fa":69,"en":70},"دوز با محرک عصب محیطی (TOF) تنظیم شود. فقط توسط فرد مجرب.","Titrate with a peripheral nerve stimulator (TOF). Experienced clinicians only.",[72],{"source":33,"section":73},"2.1",{"text":75,"refs":78},{"fa":76,"en":77},"کودک: بسته به روش بیهوشی ۰٫۴۵ mg\u002Fkg هم کافی است.","Children: 0.45 mg\u002Fkg may suffice depending on the anaesthetic technique.",[79],{"source":33,"section":63},{"id":81,"disease":47,"label":82,"population":85,"type":55,"unit":29,"dose":89,"refs":91,"durationDays":94,"allowedFormulations":95,"notes":96},"rsi",{"fa":83,"en":84},"لوله‌گذاری سریع (RSI) — ۰٫۶ تا ۱٫۲ mg\u002Fkg","Rapid sequence intubation — 0.6–1.2 mg\u002Fkg",{"minAge":86},{"value":87,"unit":88},18,"year",{"perKgPerDose":57,"perKgPerDoseMax":90,"intervalHours":58},1.2,[92],{"source":33,"section":93},"2.3",{"min":5,"max":5},[23],[97],{"text":98,"refs":99},{"fa":69,"en":70},[100],{"source":33,"section":73},{"id":102,"disease":47,"label":103,"population":106,"type":55,"unit":29,"dose":108,"refs":111,"durationDays":114,"allowedFormulations":115,"notes":116},"maint",{"fa":104,"en":105},"دوز نگهدارنده — ۰٫۱ تا ۰٫۲ mg\u002Fkg در بازگشت ۲۵٪ T1","Maintenance bolus — 0.1–0.2 mg\u002Fkg at 25% T1 recovery",{"minAge":107},{"value":87,"unit":88},{"perKgPerDose":109,"perKgPerDoseMax":110,"intervalHours":58},0.1,0.2,[112],{"source":33,"section":113},"2.4",{"min":5,"max":5},[23],[117],{"text":118,"refs":119},{"fa":69,"en":70},[120],{"source":33,"section":73},{"id":122,"disease":47,"label":123,"population":126,"type":128,"unit":40,"dose":129,"refs":131,"allowedFormulations":134,"notes":135},"inf",{"fa":124,"en":125},"انفوزیون — شروع ۱۰ تا ۱۲ mcg\u002Fkg\u002Fدقیقه پس از بازگشت اولیه","Infusion — start 10–12 mcg\u002Fkg\u002Fmin after early recovery",{"minAge":127},{"value":87,"unit":88},"infusion",{"perKgPerMin":28,"perKgPerMinMax":130},12,[132],{"source":33,"section":133},"2.5",[36],[136],{"text":137,"refs":138},{"fa":69,"en":70},[139],{"source":33,"section":73},[141],{"id":142,"severity":143,"text":144,"refs":147},"hyper","block",{"fa":145,"en":146},"حساسیت (مثلاً آنافیلاکسی) به روکورونیوم یا سایر شل‌کننده‌ها.","Hypersensitivity (e.g. anaphylaxis) to rocuronium or other neuromuscular blockers.",[148],{"source":33,"section":149},"4",[151],{"text":152,"refs":155},{"fa":153,"en":154},"آنافیلاکسی؛ فقط با بیهوشی کافی (فلج بدون آرام‌بخشی نه)؛ اشتباه دارویی کشنده است.","Anaphylaxis; only with adequate anaesthesia (no paralysis without sedation); accidental administration can be fatal.",[156,158],{"source":33,"section":157},"5",{"source":33,"section":73},[],[],[],{"status":163,"reviewer":164,"date":164},"unverified",null,[166,173,177,183],{"regimen":46,"formulation":23,"input":167,"expect":170},{"ageYears":168,"weightKg":169},40,70,{"perDose":171,"mlPerDose":172},42,4.2,{"regimen":81,"formulation":23,"input":174,"expect":175},{"ageYears":168,"weightKg":169},{"perDose":171,"mlPerDose":172,"upperPerDose":176},84,{"regimen":102,"formulation":23,"input":178,"expect":179},{"ageYears":168,"weightKg":169},{"perDose":180,"mlPerDose":181,"upperPerDose":182},7,0.7,14,{"regimen":122,"formulation":36,"input":184,"expect":185},{"ageYears":168,"weightKg":169},{"perMin":186,"mlPerHour":172,"upperPerMin":187,"upperMlPerHour":188},700,840,5.04,[190],"M03AC09",{"status":192,"forms":193,"refs":202},"registered",[194,198],{"code":195,"en":196,"fa":197},"17084","ROCURONIUM BROMIDE 50MG\u002F5ML AMP","آمپول روکورونیوم بروماید ۵۰ میلی‌گرم \u002F ۵ میلی‌لیتر",{"code":199,"en":200,"fa":201},"52073","ROCURONIUM BROMIDE INJECTION, SOLUTION PARENTERAL 10 mg\u002F1mL 10 mL","محلول تزریقی روکورونیوم بروماید ۱۰ میلی‌گرم \u002F ۱ میلی‌لیتر ۱۰ میلی‌لیتر",[203],{"source":204,"section":205,"url":206},"darooyab-generic","G-2811\u002FRocuronium","https:\u002F\u002Fwww.darooyab.ir\u002FG-2811\u002FRocuronium",{"kind":208,"refs":209,"id":212},"ANDA",[210],{"source":33,"section":211},"SPL approval \u002F marketing category","ANDA219260",[214,217,221,224],{"kind":215,"url":216,"label":212},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=219260",{"kind":218,"url":219,"label":220},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=a18fce42-0f3d-4354-845e-57c37ac3a147","FDA Rocuronium",{"kind":222,"url":223,"label":190},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=M03AC09",{"kind":225,"url":206,"label":8},"darooyab",{"pregnancy":227,"pediatric":236,"geriatric":244},{"level":228,"text":229,"quote":232,"refs":233},"caution",{"fa":230,"en":231},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Rocuronium bromide injection should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.",[234],{"source":33,"section":235},"8.1",{"level":228,"text":237,"quote":240,"refs":241},{"fa":238,"en":239},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","The use of rocuronium bromide injection has been studied in pediatric patients 3 months to 14 years of age under halothane anesthesia.",[242],{"source":33,"section":243},"8.4",{"level":228,"text":245,"quote":248,"refs":249},{"fa":246,"en":247},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Clinical experiences and recommendations for use in geriatric patients are discussed in other sections [see Dosage and Administration (2.6) , Warnings and Precautions (5.5) , Clinical Pharmacology (12.2) , and Clinical Studies (14.2) ] .",[250],{"source":33,"section":251},"8.5",1792156194379]