[{"data":1,"prerenderedAt":159},["ShallowReactive",2],{"drug-risedronate":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":36,"contraindications":57,"warnings":67,"renal":68,"monitoring":69,"interactions":70,"review":71,"examples":74,"atc":75,"iran":77,"usApproval":101,"links":107,"populations":123},"risedronate",1,{"fa":7,"en":8},"ریزدرونات","Risedronate","musculoskeletal",{"fa":11,"en":12},"بیس‌فسفونات","Bisphosphonate",[14],{"name":15,"market":16},"Atelvia","US",[18,19,20,7],"atelvia","actonel","آکتونل",[22],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-35","tablet","oral","35 mg delayed-release tablet",{"amount":28,"unit":29,"perUnit":24,"scored":30},35,"mg",false,[16],[33],{"source":34,"section":35},"fda-risedronate","3",[37],{"id":38,"disease":39,"label":40,"population":43,"type":47,"unit":29,"dose":48,"refs":52},"pmo","osteoporosis",{"fa":41,"en":42},"پوکی استخوان یائسگی — ۳۵ mg هفته‌ای یک بار","Postmenopausal osteoporosis — 35 mg once weekly",{"minAge":44},{"value":45,"unit":46},18,"year","notCalculated",{"reason":49},{"fa":50,"en":51},"هفته‌ای یک بار (نه روزانه): یک قرص ۳۵ mg صبح بلافاصله پس از صبحانه با دست‌کم ۱۲۰ mL آب؛ ۳۰ دقیقه دراز نکشد. کلسیم و ویتامین D در صورت دریافت ناکافی.","Once WEEKLY (not daily): one 35 mg tablet in the morning right after breakfast with at least 4 oz water; stay upright 30 min. Calcium and vitamin D if intake is inadequate.",[53,55],{"source":34,"section":54},"2.1",{"source":34,"section":56},"2.2",[58],{"id":59,"severity":60,"text":61,"refs":64},"ci","block",{"fa":62,"en":63},"اختلال مری که تخلیه را کند می‌کند (تنگی، آشالازی)؛ ناتوانی در نشستن یا ایستادن ۳۰ دقیقه؛ هیپوکلسمی؛ حساسیت.","Oesophageal abnormalities delaying emptying (stricture, achalasia); inability to stay upright 30 min; hypocalcaemia; hypersensitivity.",[65],{"source":34,"section":66},"4",[],[],[],[],{"status":72,"reviewer":73,"date":73},"unverified",null,[],[76],"M05BA07",{"status":78,"forms":79,"refs":96},"registered",[80,84,88,92],{"code":81,"en":82,"fa":83},"08431","RISEDRONATE 20MG TAB","قرص ریزدرونات ۲۰ میلی‌گرم",{"code":85,"en":86,"fa":87},"06737","RISEDRONATE 30MG TAB","قرص ریزدرونات ۳۰ میلی‌گرم",{"code":89,"en":90,"fa":91},"06104","RISEDRONATE 35MG TAB","قرص ریزدرونات ۳۵ میلی‌گرم",{"code":93,"en":94,"fa":95},"07662","RISEDRONATE 5MG TAB","قرص ریزدرونات ۵ میلی‌گرم",[97],{"source":98,"section":99,"url":100},"darooyab-generic","G-1444\u002FRisedronate","https:\u002F\u002Fwww.darooyab.ir\u002FG-1444\u002FRisedronate",{"kind":102,"refs":103,"id":106},"NDA authorized generic",[104],{"source":34,"section":105},"SPL approval \u002F marketing category","NDA022560",[108,111,115,118,121],{"kind":109,"url":110,"label":106},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=022560",{"kind":112,"url":113,"label":114},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=c89430be-15f1-4b8b-ab7e-738de716ee7d","FDA Risedronate DR",{"kind":116,"url":117,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa601247.html",{"kind":119,"url":120,"label":76},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=M05BA07",{"kind":122,"url":100,"label":8},"darooyab",{"pregnancy":124,"pediatric":133,"geriatric":142,"reproductive":151},{"level":125,"text":126,"quote":129,"refs":130},"avoid",{"fa":127,"en":128},"برچسب: می‌تواند به جنین آسیب بزند. در بارداری خطرناک است.","Label: can cause fetal harm. Dangerous in pregnancy.","Discontinue Risedronate sodium delayed-release when pregnancy is recognized.",[131],{"source":34,"section":132},"8.1",{"level":134,"text":135,"quote":138,"refs":139},"not-established",{"fa":136,"en":137},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Risedronate sodium delayed-release is not indicated for use in pediatric patients.",[140],{"source":34,"section":141},"8.4",{"level":143,"text":144,"quote":147,"refs":148},"caution",{"fa":145,"en":146},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Of the patients receiving Risedronate sodium delayed-release in postmenopausal osteoporosis studies, 59% were 65 and over, while 13% were 75 and over.",[149],{"source":34,"section":150},"8.5",{"level":143,"text":152,"quote":155,"refs":156},{"fa":153,"en":154},"برچسب نکته‌ای درباره بارداری، پیشگیری یا باروری زنان و مردان دارد.","Label has advice on pregnancy testing, contraception or fertility for females and males.","Infertility There are no data available in humans.",[157],{"source":34,"section":158},"8.3",1792111467306]