[{"data":1,"prerenderedAt":194},["ShallowReactive",2],{"drug-repaglinide":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":50,"contraindications":81,"warnings":91,"renal":92,"monitoring":93,"interactions":94,"review":95,"examples":98,"atc":104,"iran":106,"links":138,"populations":155,"usApproval":189},"repaglinide",1,{"fa":7,"en":8},"رپاگلینید","Repaglinide","alimentary-metabolism",{"fa":11,"en":12},"گلینید (محرک ترشح انسولین)","Glinide (insulin secretagogue)",[14],{"name":15,"market":16},"Prandin","US",[18,19,7],"prandin","novonorm",[21,35,42],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":30,"refs":31},"tab-0-5","tablet","oral","0.5 mg tablet",{"amount":27,"unit":28,"perUnit":23,"scored":29},0.5,"mg",false,[16],[32],{"source":33,"section":34},"fda-repaglinide","How Supplied",{"id":36,"form":23,"route":24,"label":37,"concentration":38,"markets":39,"refs":40},"tab-1","1 mg tablet",{"amount":5,"unit":28,"perUnit":23,"scored":29},[16],[41],{"source":33,"section":34},{"id":43,"form":23,"route":24,"label":44,"concentration":45,"markets":47,"refs":48},"tab-2","2 mg tablet",{"amount":46,"unit":28,"perUnit":23,"scored":29},2,[16],[49],{"source":33,"section":34},[51],{"id":52,"disease":53,"label":54,"population":57,"type":61,"unit":28,"dose":62,"refs":64,"limits":67,"notes":72},"std","type-2-diabetes",{"fa":55,"en":56},"دیابت نوع ۲ — ۰٫۵ mg پیش از هر وعده (HbA1c ≥ ۸٪: ۱ تا ۲ mg)","Type 2 diabetes — 0.5 mg before each meal (HbA1c ≥8%: 1–2 mg)",{"minAge":58},{"value":59,"unit":60},18,"year","fixed",{"perDose":27,"dosesPerDay":63},3,[65],{"source":33,"section":66},"2.1",{"maxPerDose":68,"maxPerDay":69,"refs":70},4,16,[71],{"source":33,"section":66},[73],{"text":74,"refs":77},{"fa":75,"en":76},"ظرف ۳۰ دقیقه پیش از غذا؛ اگر وعده حذف شد دوز هم حذف. هر هفته تا ۴ mg با هر وعده دو برابر شود. با سیکلوسپورین حداکثر ۶ mg در روز.","Within 30 min before meals; skip the dose if the meal is skipped. Double weekly up to 4 mg with each meal. With cyclosporine max 6 mg\u002Fday.",[78,79],{"source":33,"section":66},{"source":33,"section":80},"7",[82],{"id":83,"severity":84,"text":85,"refs":88},"ci","block",{"fa":86,"en":87},"مصرف همزمان جم‌فیبروزیل؛ حساسیت.","Concomitant gemfibrozil; hypersensitivity.",[89],{"source":33,"section":90},"4",[],[],[],[],{"status":96,"reviewer":97,"date":97},"unverified",null,[99],{"regimen":52,"formulation":22,"input":100,"expect":103},{"ageYears":101,"weightKg":102},60,80,{"perDose":27,"tabletsPerDoseRounded":5},[105],"A10BX02",{"status":107,"forms":108,"refs":133},"registered",[109,113,117,121,125,129],{"code":110,"en":111,"fa":112},"21635","REPAGLINIDE 0.5MG CAP","کپسول رپاگلیناید ۰٫۵ میلی‌گرم",{"code":114,"en":115,"fa":116},"04903","REPAGLINIDE 0.5MG TAB","قرص رپاگلیناید ۰٫۵ میلی‌گرم",{"code":118,"en":119,"fa":120},"21636","REPAGLINIDE 1MG CAP","کپسول رپاگلیناید ۱ میلی‌گرم",{"code":122,"en":123,"fa":124},"04904","REPAGLINIDE 1MG TAB","قرص رپاگلیناید ۱ میلی‌گرم",{"code":126,"en":127,"fa":128},"21637","REPAGLINIDE 2MG CAP","کپسول رپاگلیناید ۲ میلی‌گرم",{"code":130,"en":131,"fa":132},"04905","REPAGLINIDE 2MG TAB","قرص رپاگلیناید ۲ میلی‌گرم",[134],{"source":135,"section":136,"url":137},"darooyab-generic","G-648\u002FRepaglinide","https:\u002F\u002Fwww.darooyab.ir\u002FG-648\u002FRepaglinide",[139,143,147,150,153],{"kind":140,"url":141,"label":142},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=207209","ANDA207209",{"kind":144,"url":145,"label":146},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=7f3118ce-fcbb-4f8b-b1ba-d8cd95e5b665","FDA Repaglinide",{"kind":148,"url":149,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa600010.html",{"kind":151,"url":152,"label":105},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=A10BX02",{"kind":154,"url":137,"label":8},"darooyab",{"pregnancy":156,"lactation":165,"pediatric":173,"geriatric":181},{"level":157,"text":158,"quote":161,"refs":162},"caution",{"fa":159,"en":160},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Risk Summary Limited available data from case reports and case series with repaglinide tablets use in pregnant women have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes.",[163],{"source":33,"section":164},"8.1",{"level":157,"text":166,"quote":169,"refs":170},{"fa":167,"en":168},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary There are no data on the presence of repaglinide in human milk, the effects on the breastfeeding infant, or the effects on milk production.",[171],{"source":33,"section":172},"8.2",{"level":157,"text":174,"quote":177,"refs":178},{"fa":175,"en":176},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Safety and effectiveness have not been established in pediatric patients.",[179],{"source":33,"section":180},"8.4",{"level":157,"text":182,"quote":185,"refs":186},{"fa":183,"en":184},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","In clinical studies of 24 weeks or greater duration, 415 patients were over 65 years of age and no patients were greater than 75 years of age.",[187],{"source":33,"section":188},"8.5",{"kind":190,"refs":191,"id":142},"ANDA",[192],{"source":33,"section":193},"SPL approval \u002F marketing category",1792111466994]