[{"data":1,"prerenderedAt":186},["ShallowReactive",2],{"drug-promethazine":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":36,"contraindications":129,"warnings":150,"renal":151,"monitoring":152,"interactions":153,"review":154,"examples":157},"promethazine",1,{"fa":7,"en":8},"پرومتازین","Promethazine","antihistamines",{"fa":11,"en":12},"آنتی‌هیستامین فنوتیازینی","Phenothiazine antihistamine",[14],{"name":15,"market":16},"Phenergan","US",[18,19,7,20],"phenergan","فنرگان","پرومتازین ۲۵",[22],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-25","tablet","oral","25 mg tablet (scored)",{"amount":28,"unit":29,"perUnit":24,"scored":30},25,"mg",true,[16],[33],{"source":34,"section":35},"fda-promethazine","How Supplied",[37,59,71,83,103],{"id":38,"disease":39,"label":40,"population":43,"type":47,"unit":29,"dose":48,"refs":49,"notes":52},"allergy","allergic-conditions",{"fa":41,"en":42},"آلرژی — ۲۵ mg هنگام خواب","Allergy — 25 mg at bedtime",{"minAge":44},{"value":45,"unit":46},18,"year","fixed",{"perDose":28,"dosesPerDay":5},[50],{"source":34,"section":51},"Dosage and Administration",[53],{"text":54,"refs":57},{"fa":55,"en":56},"یا ۱۲٫۵ mg قبل از غذا و هنگام خواب؛ یا ۶٫۲۵ تا ۱۲٫۵ mg سه بار.","Or 12.5 mg before meals and at bedtime; or 6.25–12.5 mg three times daily.",[58],{"source":34,"section":51},{"id":60,"disease":61,"label":62,"population":65,"type":47,"unit":29,"dose":67,"refs":69},"motion","motion-sickness",{"fa":63,"en":64},"بیماری حرکت — بزرگسال: ۲۵ mg دو بار در روز","Motion sickness — adults: 25 mg twice daily",{"minAge":66},{"value":45,"unit":46},{"perDose":28,"dosesPerDay":68},2,[70],{"source":34,"section":51},{"id":72,"disease":61,"label":73,"population":76,"type":47,"unit":29,"dose":79,"refs":81},"motion-child",{"fa":74,"en":75},"بیماری حرکت — کودک ۲ سال به بالا: ۱۲٫۵ تا ۲۵ mg دو بار","Motion sickness — child ≥2 y: 12.5–25 mg twice daily",{"minAge":77,"maxAge":78},{"value":68,"unit":46},{"value":45,"unit":46},{"perDose":80,"perDoseMax":28,"dosesPerDay":68},12.5,[82],{"source":34,"section":51},{"id":84,"disease":85,"label":86,"population":89,"type":47,"unit":29,"dose":91,"refs":94,"notes":96},"nv-adult","nausea-vomiting",{"fa":87,"en":88},"تهوع و استفراغ — بزرگسال: ۲۵ mg","Nausea and vomiting — adults: 25 mg",{"minAge":90},{"value":45,"unit":46},{"perDose":28,"dosesPerDay":92,"intervalHours":93},4,6,[95],{"source":34,"section":51},[97],{"text":98,"refs":101},{"fa":99,"en":100},"پیشگیری (مثلاً پس از جراحی): ۲۵ mg هر ۴ تا ۶ ساعت در صورت نیاز.","Prophylaxis (e.g. postoperative): 25 mg every 4–6 h as needed.",[102],{"source":34,"section":51},{"id":104,"disease":85,"label":105,"population":108,"type":111,"unit":29,"dose":112,"refs":114,"limits":116,"notes":122},"nv-child",{"fa":106,"en":107},"تهوع و استفراغ — کودک ۲ سال به بالا: ۰٫۵ mg\u002Fپوند (≈۱٫۱ mg\u002Fkg)","Nausea and vomiting — child ≥2 y: 0.5 mg\u002Flb (≈1.1 mg\u002Fkg)",{"minAge":109,"maxAge":110},{"value":68,"unit":46},{"value":45,"unit":46},"weightBased",{"perKgPerDose":113,"intervalHours":93},1.1,[115],{"source":34,"section":51},{"maxPerDose":28,"refs":117},[118],{"source":34,"section":51,"note":119},{"fa":120,"en":121},"Doz دوز مؤثر متوسط (۲۵ mg) را سقف هر دوز گرفته؛ برچسب آن را حداکثر نگفته","Doz uses the average adult\u002Fchild effective dose (25 mg) as a per-dose ceiling; not stated as a maximum",[123],{"text":124,"refs":127},{"fa":125,"en":126},"۰٫۵ mg به‌ازای هر پوند؛ تبدیل به mg\u002Fkg را Doz انجام داده. در استفراغ با علت نامعلوم در کودکان استفاده نشود.","0.5 mg per pound; conversion to mg\u002Fkg done by Doz. Do not use for vomiting of unknown cause in children.",[128],{"source":34,"section":51},[130,143],{"id":131,"severity":132,"rule":133,"text":135,"refs":138},"under-2","block",{"maxAge":134},{"value":68,"unit":46},{"fa":136,"en":137},"هشدار جعبه‌ای: زیر ۲ سال منع مصرف (دپرسیون تنفسی کشنده).","Boxed warning: contraindicated under 2 years (fatal respiratory depression).",[139,141],{"source":34,"section":140},"Contraindications",{"source":34,"section":142},"Boxed Warning",{"id":144,"severity":132,"text":145,"refs":148},"ci",{"fa":146,"en":147},"کما؛ حساسیت به فنوتیازین‌ها؛ درمان علائم تنفسی تحتانی از جمله آسم.","Coma; hypersensitivity to phenothiazines; lower respiratory symptoms including asthma.",[149],{"source":34,"section":140},[],[],[],[],{"status":155,"reviewer":156,"date":156},"unverified",null,[158,163,167,172,175,181],{"regimen":38,"formulation":23,"input":159,"expect":162},{"ageYears":160,"weightKg":161},30,70,{"perDose":28},{"regimen":60,"formulation":23,"input":164,"expect":165},{"ageYears":160,"weightKg":161},{"perDay":166},50,{"regimen":72,"formulation":23,"input":168,"expect":170},{"ageYears":169,"weightKg":28},8,{"perDose":80,"tabletsPerDoseRounded":171},0.5,{"regimen":84,"formulation":23,"input":173,"expect":174},{"ageYears":160,"weightKg":161},{"perDose":28},{"regimen":104,"formulation":23,"input":176,"expect":179},{"ageYears":177,"weightKg":178},5,11.5,{"perDose":180,"tabletsPerDoseRounded":171},12.65,{"regimen":104,"formulation":23,"input":182,"expect":185},{"ageYears":183,"weightKg":184},12,40,{"perDose":28},1792078539838]