[{"data":1,"prerenderedAt":185},["ShallowReactive",2],{"drug-piroxicam":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":12,"synonyms":16,"formulations":19,"regimens":42,"contraindications":65,"warnings":75,"renal":83,"monitoring":84,"interactions":85,"review":86,"examples":89,"atc":95,"iran":97,"usApproval":121,"links":127,"populations":143},"piroxicam",1,{"fa":7,"en":8},"پیروکسیکام","Piroxicam","musculoskeletal",{"fa":11,"en":11},"NSAID",[13],{"name":14,"market":15},"Feldene","US",[17,18,7],"feldene","فلدن",[20,34],{"id":21,"form":22,"route":23,"label":24,"concentration":25,"markets":29,"refs":30},"cap-10","capsule","oral","10 mg capsule",{"amount":26,"unit":27,"perUnit":22,"scored":28},10,"mg",false,[15],[31],{"source":32,"section":33},"fda-piroxicam","3",{"id":35,"form":22,"route":23,"label":36,"concentration":37,"markets":39,"refs":40},"cap-20","20 mg capsule",{"amount":38,"unit":27,"perUnit":22,"scored":28},20,[15],[41],{"source":32,"section":33},[43],{"id":44,"disease":45,"label":46,"population":49,"type":53,"unit":27,"dose":54,"refs":55,"notes":58},"arthritis","osteoarthritis",{"fa":47,"en":48},"استئوآرتریت و آرتریت روماتوئید — ۲۰ mg یک بار در روز","OA and RA — 20 mg once daily",{"minAge":50},{"value":51,"unit":52},18,"year","fixed",{"perDose":38,"dosesPerDay":5},[56],{"source":32,"section":57},"2",[59],{"text":60,"refs":63},{"fa":61,"en":62},"در صورت تمایل می‌توان دوز روزانه را تقسیم کرد. سطح پایدار پس از ۷ تا ۱۲ روز.","The daily dose may be divided. Steady state after 7–12 days.",[64],{"source":32,"section":57},[66],{"id":67,"severity":68,"text":69,"refs":72},"nsaid","block",{"fa":70,"en":71},"حساسیت؛ سابقه آسم، کهیر یا واکنش آلرژیک با آسپرین یا NSAID؛ درد حین جراحی CABG.","Hypersensitivity; history of asthma, urticaria or allergic reaction to aspirin or NSAIDs; perioperative pain in CABG.",[73],{"source":32,"section":74},"4",[76],{"text":77,"refs":80},{"fa":78,"en":79},"هشدار جعبه‌ای: خطر حوادث قلبی‌عروقی ترومبوتیک و خونریزی، زخم و سوراخ شدن دستگاه گوارش.","Boxed warning: risk of serious thrombotic cardiovascular events and GI bleeding, ulceration and perforation.",[81],{"source":32,"section":82},"Boxed Warning",[],[],[],{"status":87,"reviewer":88,"date":88},"unverified",null,[90],{"regimen":44,"formulation":35,"input":91,"expect":94},{"ageYears":92,"weightKg":93},55,75,{"perDose":38,"tabletsPerDoseRounded":5},[96],"M01AC01",{"status":98,"forms":99,"refs":116},"registered",[100,104,108,112],{"code":101,"en":102,"fa":103},"01016","PIROXICAM 0.5% GEL","ژل پیروکسیکام ۰٫۵ درصد",{"code":105,"en":106,"fa":107},"01017","PIROXICAM 10MG CAP","کپسول پیروکسیکام ۱۰ میلی‌گرم",{"code":109,"en":110,"fa":111},"02094","PIROXICAM 20MG SUPP","شیاف پیروکسیکام ۲۰ میلی‌گرم",{"code":113,"en":114,"fa":115},"01018","PIROXICAM 20MG\u002F1ML AMP","آمپول پیروکسیکام ۲۰ میلی‌گرم \u002F ۱ میلی‌لیتر",[117],{"source":118,"section":119,"url":120},"darooyab-generic","G-171\u002FPiroxicam","https:\u002F\u002Fwww.darooyab.ir\u002FG-171\u002FPiroxicam",{"kind":122,"refs":123,"id":126},"ANDA",[124],{"source":32,"section":125},"SPL approval \u002F marketing category","ANDA074131",[128,131,135,138,141],{"kind":129,"url":130,"label":126},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=074131",{"kind":132,"url":133,"label":134},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=f1123fe1-b79c-430b-8548-08cd6e518482","FDA Piroxicam",{"kind":136,"url":137,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa684045.html",{"kind":139,"url":140,"label":96},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=M01AC01",{"kind":142,"url":120,"label":8},"darooyab",{"pregnancy":144,"lactation":153,"pediatric":162,"geriatric":170,"reproductive":177},{"level":145,"text":146,"quote":149,"refs":150},"avoid",{"fa":147,"en":148},"برچسب: می‌تواند به جنین آسیب بزند. در بارداری خطرناک است.","Label: can cause fetal harm. Dangerous in pregnancy.","Clinical Considerations Fetal\u002FNeonatal Adverse Reactions Premature Closure of Fetal Ductus Arteriosus: Avoid use of NSAIDs in women at about 30 weeks gestation and later in pregnancy, because NSAIDs, including piroxicam, can cause premature closure of the fetal ductus arteriosus ( see Data ).",[151],{"source":32,"section":152},"8.1",{"level":154,"text":155,"quote":158,"refs":159},"caution",{"fa":156,"en":157},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary Limited data from 2 published reports that included a total of 6 breastfeeding women and 2 infants showed piroxicam is excreted in human milk at approximately 1% to 3% of the maternal concentration.",[160],{"source":32,"section":161},"8.2",{"level":154,"text":163,"quote":166,"refs":167},{"fa":164,"en":165},"برچسب برای کودکان شرط، محدودیت سنی یا نکته دارد؛ جمله برچسب در زیر آمده است.","The label has conditions, age limits or notes for children; the label sentence is quoted below.","Piroxicam has not been investigated in pediatric patients.",[168],{"source":32,"section":169},"8.4",{"level":154,"text":171,"quote":174,"refs":175},{"fa":172,"en":173},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Elderly patients and patients with a prior history of peptic ulcer disease and\u002For GI bleeding are at greater risk for serious GI events [see Warnings and Precautions ( 5.2 )] .",[176],{"source":32,"section":82},{"level":154,"text":178,"quote":181,"refs":182},{"fa":179,"en":180},"برچسب نکته‌ای درباره بارداری، پیشگیری یا باروری زنان و مردان دارد.","Label has advice on pregnancy testing, contraception or fertility for females and males.","Infertility Females Based on the mechanism of action, the use of prostaglandin-mediated NSAIDs, including piroxicam, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women.",[183],{"source":32,"section":184},"8.3",1792111464605]