[{"data":1,"prerenderedAt":158},["ShallowReactive",2],{"drug-oxytocin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":22,"regimens":36,"contraindications":77,"warnings":87,"renal":95,"monitoring":96,"interactions":97,"review":98,"examples":101,"atc":107,"iran":109,"links":125,"populations":143,"usApproval":153},"oxytocin",1,{"fa":7,"en":8},"اکسی‌توسین","Oxytocin","systemic-hormones",{"fa":11,"en":12},"هورمون منقبض‌کننده رحم","Uterotonic hormone",[14],{"name":15,"market":16},"Pitocin","US",[18,19,20,21],"pitocin","syntocinon","سنتوسینون","اکسی توسین",[23],{"id":24,"form":25,"route":26,"label":27,"concentration":28,"markets":31,"refs":32},"vial-10","injection","im","10 units\u002FmL injection",{"amount":29,"unit":30,"perVolumeMl":5},10,"unit",[16],[33],{"source":34,"section":35},"fda-pitocin","How Supplied",[37,60],{"id":38,"disease":39,"label":40,"population":43,"type":47,"unit":30,"dose":48,"refs":49,"durationDays":52,"notes":53},"pph-im","postpartum-hemorrhage",{"fa":41,"en":42},"خونریزی پس از زایمان — ۱۰ واحد عضلانی پس از خروج جفت","Postpartum haemorrhage — 10 units IM after delivery of the placenta",{"minAge":44},{"value":45,"unit":46},18,"year","fixed",{"perDose":29,"dosesPerDay":5},[50],{"source":34,"section":51},"Dosage and Administration — B. Control of Postpartum Uterine Bleeding",{"min":5,"max":5},[54],{"text":55,"refs":58},{"fa":56,"en":57},"وریدی: ۱۰ تا ۴۰ واحد به سرم در جریان (حداکثر ۴۰ واحد در ۱۰۰۰ mL) و تنظیم سرعت برای حفظ انقباض رحم.","IV: add 10–40 units to the running infusion (max 40 units per 1,000 mL) and adjust the rate to sustain uterine contraction.",[59],{"source":34,"section":51},{"id":61,"disease":62,"label":63,"population":66,"type":68,"unit":69,"dose":70,"refs":74},"induction","labor-induction",{"fa":64,"en":65},"القا یا تقویت زایمان — فقط انفوزیون وریدی با پمپ","Induction or augmentation of labour — IV infusion by pump only",{"minAge":67},{"value":45,"unit":46},"notCalculated","mg",{"reason":71},{"fa":72,"en":73},"برچسب: ۱ ویال ۱۰ واحدی در ۱۰۰۰ mL سالین یا رینگر لاکتات (۱۰ میلی‌واحد\u002FmL). شروع ۰٫۵ تا ۱ میلی‌واحد\u002Fدقیقه (۳ تا ۶ mL\u002Fساعت)، هر ۳۰ تا ۶۰ دقیقه ۱ تا ۲ میلی‌واحد\u002Fدقیقه افزایش تا الگوی انقباض مطلوب. فقط در بیمارستان با پایش؛ برای القای انتخابی بدون اندیکاسیون نیست.","Label: one 10-unit vial in 1,000 mL saline or Ringer’s lactate (10 mU\u002FmL). Start 0.5–1 mU\u002Fmin (3–6 mL\u002Fh), increase by 1–2 mU\u002Fmin every 30–60 min until the desired contraction pattern. Hospital with monitoring only; not for elective induction without indication.",[75],{"source":34,"section":76},"Dosage and Administration",[78],{"id":79,"severity":80,"text":81,"refs":84},"ante","block",{"fa":82,"en":83},"پیش از زایمان: عدم تناسب سر و لگن، وضعیت نامناسب جنین، دیسترس جنین بدون زایمان قریب‌الوقوع، رحم پرکار، منع زایمان طبیعی (جفت سرراهی کامل، وازا پرویا، هرپس فعال تناسلی، پرولاپس بند ناف)، حساسیت.","Antepartum: cephalopelvic disproportion, unfavourable fetal position, fetal distress with delivery not imminent, hyperactive uterus, contraindication to vaginal delivery (complete placenta praevia, vasa praevia, active genital herpes, cord prolapse), hypersensitivity.",[85],{"source":34,"section":86},"Contraindications",[88],{"text":89,"refs":92},{"fa":90,"en":91},"هشدار جعبه‌ای: برای القای انتخابی زایمان (بدون اندیکاسیون پزشکی) اندیکاسیون ندارد.","Boxed warning: not indicated for elective induction of labour.",[93],{"source":34,"section":94},"Boxed Warning",[],[],[],{"status":99,"reviewer":100,"date":100},"unverified",null,[102],{"regimen":38,"formulation":24,"input":103,"expect":106},{"ageYears":104,"weightKg":105},28,70,{"perDose":29,"mlPerDose":5},[108],"H01BB02",{"status":110,"forms":111,"refs":120},"registered",[112,116],{"code":113,"en":114,"fa":115},"00939","OXYTOCIN 10U\u002F1ML AMP","آمپول اکسیتوسین ۱۰ واحد \u002F ۱ میلی‌لیتر",{"code":117,"en":118,"fa":119},"00940","OXYTOCIN 5U\u002F1ML AMP","آمپول اکسیتوسین ۵ واحد \u002F ۱ میلی‌لیتر",[121],{"source":122,"section":123,"url":124},"darooyab-generic","G-2711\u002FOxytocin","https:\u002F\u002Fwww.darooyab.ir\u002FG-2711\u002FOxytocin",[126,130,134,138,141],{"kind":127,"url":128,"label":129},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=018261","NDA018261",{"kind":131,"url":132,"label":133},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=6e5a66fc-e507-497c-b5ce-44a8c95898ad","FDA Pitocin",{"kind":135,"url":136,"label":137},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa682685.html","Oxytocin Injection",{"kind":139,"url":140,"label":108},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=H01BB02",{"kind":142,"url":124,"label":8},"darooyab",{"pregnancy":144},{"level":145,"text":146,"quote":149,"refs":150},"caution",{"fa":147,"en":148},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Teratogenic Effects Animal reproduction studies have not been conducted with oxytocin.",[151],{"source":34,"section":152},"Pregnancy",{"kind":154,"refs":155,"id":129},"NDA",[156],{"source":34,"section":157},"SPL approval \u002F marketing category",1792111463581]