[{"data":1,"prerenderedAt":171},["ShallowReactive",2],{"drug-ofloxacin-eye":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":20,"regimens":33,"contraindications":58,"warnings":68,"renal":69,"monitoring":70,"interactions":71,"review":72,"examples":75,"atc":81,"iran":83,"links":115,"populations":130,"usApproval":166},"ofloxacin-eye",1,{"fa":7,"en":8},"قطره چشمی افلوکساسین","Ofloxacin eye drops","sensory-organs",{"fa":11,"en":12},"فلوروکینولون چشمی","Ophthalmic fluoroquinolone",[14],{"name":15,"market":16},"Ocuflox","US",[18,19],"ocuflox","افلوکساسین چشمی",[21],{"id":22,"form":23,"route":24,"label":25,"concentration":26,"markets":28,"refs":29},"drops","eye-drops","ophthalmic","0.3% ophthalmic solution",{"amount":5,"unit":27,"perUnit":27},"drop",[16],[30],{"source":31,"section":32},"fda-ofloxacineye","How Supplied",[34],{"id":35,"disease":36,"label":37,"population":40,"type":43,"unit":27,"dose":44,"refs":46,"notes":49},"conj","bacterial-conjunctivitis",{"fa":38,"en":39},"کونژنکتیویت باکتریایی — روز ۱ و ۲: ۱ تا ۲ قطره هر ۲ تا ۴ ساعت","Bacterial conjunctivitis — days 1–2: 1–2 drops every 2–4 h",{"minAge":41},{"value":5,"unit":42},"year","fixed",{"perDose":5,"dosesPerDay":45},6,[47],{"source":31,"section":48},"Dosage and Administration",[50],{"text":51,"refs":54},{"fa":52,"en":53},"روز ۳ تا ۷: ۱ تا ۲ قطره چهار بار در روز. زیر ۱ سال ثابت نشده. زخم قرنیه رژیم جداگانه دارد.","Days 3–7: 1–2 drops four times daily. Not established under 1 y. Corneal ulcer has a separate regimen.",[55,56],{"source":31,"section":48},{"source":31,"section":57},"Pediatric Use",[59],{"id":60,"severity":61,"text":62,"refs":65},"hyper","block",{"fa":63,"en":64},"حساسیت به افلوکساسین یا سایر کینولون‌ها.","Hypersensitivity to ofloxacin or other quinolones.",[66],{"source":31,"section":67},"Contraindications",[],[],[],[],{"status":73,"reviewer":74,"date":74},"unverified",null,[76],{"regimen":35,"formulation":22,"input":77,"expect":80},{"ageYears":78,"weightKg":79},20,60,{"perDose":5},[82],"S01AE01",{"status":84,"forms":85,"refs":110},"registered",[86,90,94,98,102,106],{"code":87,"en":88,"fa":89},"02446","OFLOXACIN  0.30% OTIC DROP","قطره گوشی افلوکساسین ۰٫۳۰ درصد",{"code":91,"en":92,"fa":93},"00929","OFLOXACIN 100MG TAB","قرص افلوکساسین ۱۰۰ میلی‌گرم",{"code":95,"en":96,"fa":97},"00930","OFLOXACIN 200MG FC TAB","قرص روکش‌دار افلوکساسین ۲۰۰ میلی‌گرم",{"code":99,"en":100,"fa":101},"02009","OFLOXACIN 300MG FC TAB","قرص روکش‌دار افلوکساسین ۳۰۰ میلی‌گرم",{"code":103,"en":104,"fa":105},"08636","OFLOXACIN 400MG FC TAB","قرص روکش‌دار افلوکساسین ۴۰۰ میلی‌گرم",{"code":107,"en":108,"fa":109},"52369","OFLOXACIN SOLUTION, DROPS OPHTHALMIC 3 mg\u002F1mL 5 mL","قطره چشمی افلوکساسین ۳ میلی‌گرم \u002F ۱ میلی‌لیتر ۵ میلی‌لیتر",[111],{"source":112,"section":113,"url":114},"darooyab-generic","G-461\u002FOfloxacin","https:\u002F\u002Fwww.darooyab.ir\u002FG-461\u002FOfloxacin",[116,120,124,127],{"kind":117,"url":118,"label":119},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=076513","ANDA076513",{"kind":121,"url":122,"label":123},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=5117d567-2004-c5ed-1391-f8831864696f","FDA Ofloxacin eye",{"kind":125,"url":126,"label":82},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=S01AE01",{"kind":128,"url":114,"label":129},"darooyab","Ofloxacin",{"pregnancy":131,"lactation":140,"pediatric":149,"geriatric":157},{"level":132,"text":133,"quote":136,"refs":137},"caution",{"fa":134,"en":135},"برچسب خطر مشخصی برای بارداری ذکر نکرده یا داده کافی ندارد؛ فقط در صورت لزوم و با نظر پزشک.","Label states no clear risk or has limited data; use only if needed, under medical advice.","Ofloxacin ophthalmic solution should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.",[138],{"source":31,"section":139},"Pregnancy",{"level":141,"text":142,"quote":145,"refs":146},"avoid",{"fa":143,"en":144},"برچسب: شیردهی توصیه نمی‌شود یا باید بین دارو و شیردهی یکی انتخاب شود.","Label: breastfeeding not recommended, or choose between the drug and breastfeeding.","Because of the potential for serious adverse reactions from ofloxacin in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.",[147],{"source":31,"section":148},"Nursing Mothers",{"level":150,"text":151,"quote":154,"refs":155},"not-established",{"fa":152,"en":153},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Safety and effectiveness in infants below the age of one year have not been established.",[156],{"source":31,"section":57},{"level":158,"text":159,"quote":162,"refs":163},"ok",{"fa":160,"en":161},"برچسب: در سالمندان تفاوت یا تنظیم دوز خاصی ذکر نشده.","Label: no specific difference or dose adjustment stated for older adults.","No overall differences in safety or effectiveness have been observed between elderly and younger patients.",[164],{"source":31,"section":165},"Geriatric Use",{"kind":167,"refs":168,"id":119},"ANDA",[169],{"source":31,"section":170},"SPL approval \u002F marketing category",1792092041544]