[{"data":1,"prerenderedAt":201},["ShallowReactive",2],{"drug-moxifloxacin":3},{"id":4,"schemaVersion":5,"name":6,"category":9,"class":10,"brands":13,"synonyms":17,"formulations":21,"regimens":36,"contraindications":68,"warnings":88,"renal":96,"monitoring":97,"interactions":98,"review":107,"examples":110,"atc":119,"iran":121,"links":141,"populations":161,"usApproval":196},"moxifloxacin",1,{"fa":7,"en":8},"موکسی‌فلوکساسین","Moxifloxacin","anti-infectives",{"fa":11,"en":12},"فلوروکینولون","Fluoroquinolone",[14],{"name":15,"market":16},"Avelox","US",[18,19,20],"avelox","آولوکس","موکسی فلوکساسین",[22],{"id":23,"form":24,"route":25,"label":26,"concentration":27,"markets":31,"refs":32},"tab-400","tablet","oral","400 mg tablet",{"amount":28,"unit":29,"perUnit":24,"scored":30},400,"mg",false,[16],[33],{"source":34,"section":35},"fda-moxifloxacin","3",[37,55],{"id":38,"disease":39,"label":40,"population":43,"type":47,"unit":29,"dose":48,"refs":49,"durationDays":52},"cap","community-acquired-pneumonia",{"fa":41,"en":42},"پنومونی اکتسابی — ۴۰۰ mg روزانه، ۷ تا ۱۴ روز","CAP — 400 mg once daily, 7–14 days",{"minAge":44},{"value":45,"unit":46},18,"year","fixed",{"perDose":28,"dosesPerDay":5},[50],{"source":34,"section":51},"2.1",{"min":53,"max":54},7,14,{"id":56,"disease":57,"label":58,"population":61,"type":47,"unit":29,"dose":63,"refs":64,"durationDays":66},"sinusitis","acute-bacterial-sinusitis",{"fa":59,"en":60},"سینوزیت باکتریایی حاد — ۴۰۰ mg روزانه، ۱۰ روز","Acute bacterial sinusitis — 400 mg once daily, 10 days",{"minAge":62},{"value":45,"unit":46},{"perDose":28,"dosesPerDay":5},[65],{"source":34,"section":51},{"min":67,"max":67},10,[69,78],{"id":70,"severity":71,"text":72,"refs":75},"hyper","block",{"fa":73,"en":74},"حساسیت به موکسی‌فلوکساسین یا هر کینولون.","Hypersensitivity to moxifloxacin or any quinolone.",[76],{"source":34,"section":77},"4",{"id":79,"severity":71,"rule":80,"text":82,"refs":85},"child",{"maxAge":81},{"value":45,"unit":46},{"fa":83,"en":84},"زیر ۱۸ سال اثربخشی ثابت نشده.","Effectiveness under 18 not established.",[86],{"source":34,"section":87},"8.4",[89],{"text":90,"refs":93},{"fa":91,"en":92},"هشدار جعبه‌ای فلوروکینولون‌ها: پارگی تاندون، نوروپاتی محیطی، اثرات CNS، تشدید میاستنی؛ برای سینوزیت و برونشیت فقط اگر گزینه دیگری نیست.","Fluoroquinolone boxed warning: tendon rupture, peripheral neuropathy, CNS effects, myasthenia exacerbation; for sinusitis\u002Fbronchitis only if no alternative.",[94],{"source":34,"section":95},"Boxed Warning",[],[],[99],{"with":100,"text":101,"refs":104},"cations",{"fa":102,"en":103},"۴ ساعت قبل یا ۸ ساعت بعد از منیزیم، آلومینیوم، آهن، روی، آنتی‌اسید و مولتی‌ویتامین.","Take 4 h before or 8 h after magnesium, aluminium, iron, zinc, antacids or multivitamins.",[105],{"source":34,"section":106},"2.2",{"status":108,"reviewer":109,"date":109},"unverified",null,[111,116],{"regimen":38,"formulation":23,"input":112,"expect":115},{"ageYears":113,"weightKg":114},40,70,{"perDose":28,"tabletsPerDoseRounded":5},{"regimen":56,"formulation":23,"input":117,"expect":118},{"ageYears":113,"weightKg":114},{"perDose":28},[120],"J01MA14",{"status":122,"forms":123,"refs":136},"registered",[124,128,132],{"code":125,"en":126,"fa":127},"14266","MOXIFLOXACIN 0.5% 5ML OPH DROP","قطره چشمی موکسی‌فلوکساسین ۰٫۵ درصد ۵ میلی‌لیتر",{"code":129,"en":130,"fa":131},"08277","MOXIFLOXACIN HCL 400MG TAB","قرص موکسی‌فلوکساسین هیدروکلراید ۴۰۰ میلی‌گرم",{"code":133,"en":134,"fa":135},"52529","MOXIFLOXACIN SOLUTION, DROPS OPHTHALMIC 0.5 % 0.5 mL","قطره چشمی موکسی‌فلوکساسین ۰٫۵ درصد ۰٫۵ میلی‌لیتر",[137],{"source":138,"section":139,"url":140},"darooyab-generic","G-444\u002FMoxifloxacin","https:\u002F\u002Fwww.darooyab.ir\u002FG-444\u002FMoxifloxacin",[142,146,150,153,156,159],{"kind":143,"url":144,"label":145},"fda","https:\u002F\u002Fwww.accessdata.fda.gov\u002Fscripts\u002Fcder\u002Fdaf\u002Findex.cfm?event=overview.process&ApplNo=202632","ANDA202632",{"kind":147,"url":148,"label":149},"dailymed","https:\u002F\u002Fdailymed.nlm.nih.gov\u002Fdailymed\u002FdrugInfo.cfm?setid=f34c08e6-fe74-4de3-9e36-a82c3c1c183b","FDA Moxifloxacin",{"kind":151,"url":152,"label":8},"medlineplus","https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa600002.html",{"kind":151,"url":154,"label":155},"https:\u002F\u002Fmedlineplus.gov\u002Fdruginfo\u002Fmeds\u002Fa608030.html","Moxifloxacin Injection",{"kind":157,"url":158,"label":120},"who-atc","https:\u002F\u002Fatcddd.fhi.no\u002Fatc_ddd_index\u002F?code=J01MA14",{"kind":160,"url":140,"label":8},"darooyab",{"pregnancy":162,"lactation":171,"pediatric":180,"geriatric":188},{"level":163,"text":164,"quote":167,"refs":168},"avoid",{"fa":165,"en":166},"برچسب: می‌تواند به جنین آسیب بزند. در بارداری خطرناک است.","Label: can cause fetal harm. Dangerous in pregnancy.","Based on animal studies with moxifloxacin, moxifloxacin hydrochloride may cause fetal harm.",[169],{"source":34,"section":170},"8.1",{"level":172,"text":173,"quote":176,"refs":177},"caution",{"fa":174,"en":175},"برچسب: در شیردهی با احتیاط؛ متن برچسب را ببینید.","Label: use with caution while breastfeeding; see the label text.","Risk Summary It is not known if moxifloxacin is present in human milk.",[178],{"source":34,"section":179},"8.2",{"level":181,"text":182,"quote":185,"refs":186},"not-established",{"fa":183,"en":184},"برچسب: ایمنی و اثربخشی در کودکان ثابت نشده است.","Label: safety and effectiveness in children have not been established.","Effectiveness in pediatric patients and adolescents less than 18 years of age has not been established.",[187],{"source":34,"section":87},{"level":172,"text":189,"quote":192,"refs":193},{"fa":190,"en":191},"برچسب: در سالمندان با احتیاط و معمولاً از دوز پایین شروع شود.","Label: use with caution in older adults, usually starting at the low end of the dose range.","Caution should be used when prescribing moxifloxacin hydrochloride to elderly patients especially those on corticosteroids.",[194],{"source":34,"section":195},"8.5",{"kind":197,"refs":198,"id":145},"ANDA",[199],{"source":34,"section":200},"SPL approval \u002F marketing category",1792092040808]